Not really sure. I have an upcoming appt with a nephrologist to help, but I am anxious. I had some type of nephritis as a teen. The last was combined with tonsilitis and saw me drop to 98 lbs from 165 in a few short weeks (35 the first 3 days). Now, more than 40 years later, my latest blood and urine tests are all alarming, with gfr at 40, microalbumin/creatinine at 69.6, creatinine at 1.72, creatinine, urine at 195.3 and microalbumin, ur, qn detection limit at 135.9. How serious is this and how concerned should I be? I also had an exploratory exam which shows some blood and urine will always be present because of thin bladder tissue walls.