Dear Sir, Hi & Welcome. Sorry to know that your granddaughter is suffering from nephrotic syndrome. It is a kidney disease that causes too much excretion protein through urine. It is more common among children & has both primary and secondary causes. It is usually caused by damage to the clusters of small blood vessels in the kidneys that filter waste & excess water from the blood. This results in development of edema (swelling) particularly in the feet, ankles, abdomen & also increases the risk of other health problems like infection, hypertension, thrombosis (clot in the blood vessels), etc. Treatment for nephrotic syndrome includes treating the underlying condition that s causing it and taking medications for the complications as listed above. Kindly send all the reports for proper interpretation and advice. Best wishes.