Hi there, I have understood your concern. I will suggest you the best possible treatment options. 1. As you might be aware that in a woman with regular cycles day 10 to 20 of the cycle is the most fertile period of cycle. If you happen to have unprotected sex act in the fertile period at least on alternate days, then you stand chance to get pregnant. 2. Even a single sexual activity right on the day of ovulation can cause pregnancy. 3. As precautions to minimise problems during pregnancy, I will suggest you the following for your wife- Please opt for a healthy diet and regular exercise regimen . Include more portions of fruits, salads and vegetables in daily diet. Drink plenty of water in the day. Avoid deep fried foods , bakery products and refined sugars. Use of vitamin B 12, Folic acid and Omega 3 supplements at least 3 months before you plan to get pregnant. This helps to prevent many problems during pregnancy and delivery I hope this answer helps you. Thanks. Dr. Purushottam Neurgaonkar