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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Is The Difference Between Iron Ferrous Sulfate And Bisglycinate Drugs?

my daughter is anemic and has been taking iron supplement, iron biscglycinate 50 mg 2 x day. what is difference between iron ferrous sulfate and biscgycinate. does this dosage sound correct? how much elemental iron does this have in a 50 mg dose of biscgycinate?
Mon, 8 Jun 2015
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Pathologist and Microbiologist 's  Response
Hi I did review your concern.
Both iron sulfate and bisglycinate have different amounts of elemental iron and that relates with toxicity and abdominal side effects as well as amount of response that occurs. Higher the elemental iron, higher the toxicity but higher the response.

So a balance is required. Iron bisglycinate 50 mg bid is a right dose to start with and the best way to measure response is to get a reticulocyte count at 1week after response. it should rise in response to iron therapy.
Also iron bisglycinate has 20% w/w elemental iron in it just like ferrous sulfate. It has more bioavailability and known to cause less Gastrointestinal disturbances as compared to ferrous sulfate.
I hope this helps
Wish you all the best
Thank you for choosing healthcaremagic
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What Is The Difference Between Iron Ferrous Sulfate And Bisglycinate Drugs?

Hi I did review your concern. Both iron sulfate and bisglycinate have different amounts of elemental iron and that relates with toxicity and abdominal side effects as well as amount of response that occurs. Higher the elemental iron, higher the toxicity but higher the response. So a balance is required. Iron bisglycinate 50 mg bid is a right dose to start with and the best way to measure response is to get a reticulocyte count at 1week after response. it should rise in response to iron therapy. Also iron bisglycinate has 20% w/w elemental iron in it just like ferrous sulfate. It has more bioavailability and known to cause less Gastrointestinal disturbances as compared to ferrous sulfate. I hope this helps Wish you all the best Thank you for choosing healthcaremagic