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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Is The Probable Cause For Reduction Of Weight?

sir my father is having diabetes for past one year he is also having portal hypertension with cirrhosis for past 18 yrs.now his weight is reduced upto 6kg in one month.AFP done it showed negative.pls help me what's the most probable cause for reduction of weight
Thu, 10 Jul 2014
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General & Family Physician,  's  Response
hi iam Dr.Nallammai

welcome to healthcare magic

as ur dad is having cirrhosis fr past 18 yrs..it is a risk factor for hepatocellular carcinoma(hcc)..the thing u should do to diagnose hcc early is USG every 6 months and AFP also.. as his AFP was negative it doesnt mean that he doesnt mean that he has not developed hcc..since that test has poor sensitivity and poor specificity..

as he had gross wt loss..i suggest you to do USG every 6 months and liver biopsy once..it is not to frighten u..it is to do early diagnosis and treat him early..

wt loss may also be due to diabetes treatment..but not this gross..

so it is good to investigate him for hcc
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What Is The Probable Cause For Reduction Of Weight?

hi iam Dr.Nallammai welcome to healthcare magic as ur dad is having cirrhosis fr past 18 yrs..it is a risk factor for hepatocellular carcinoma(hcc)..the thing u should do to diagnose hcc early is USG every 6 months and AFP also.. as his AFP was negative it doesnt mean that he doesnt mean that he has not developed hcc..since that test has poor sensitivity and poor specificity.. as he had gross wt loss..i suggest you to do USG every 6 months and liver biopsy once..it is not to frighten u..it is to do early diagnosis and treat him early.. wt loss may also be due to diabetes treatment..but not this gross.. so it is good to investigate him for hcc