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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Is The Reason For A Newborn Being Tested Positive For Cocaine?

My newborn grandson was tested in the hospital for drugs in his stool sample. An associated organization says that it tested positive for cocaine. What is the testing process in these cases? Can they be misread? Is there a possibility that other substances contain cocaine type results?
Mon, 20 Jan 2014
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Psychiatrist,  's  Response
hi
thanks for healthcare magic

benzoylecgonine is metabolite used to detect cocaine in blood, urine and meconium. Confirmation assays for meconium are more difficult than those for urine. Although HPLC has been used. Recoveries of drugs from meconium can be low (30–50%), which means that selection of proper internal standards is important. Fortunately, deuterated internal standards for most of drugs of abuse are now available. In ur case test may be due to prenatal exposure of cocaine. Chances of false positive in this case is less. For recent intake u can try cocaine level in hair.

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What Is The Reason For A Newborn Being Tested Positive For Cocaine?

hi thanks for healthcare magic benzoylecgonine is metabolite used to detect cocaine in blood, urine and meconium. Confirmation assays for meconium are more difficult than those for urine. Although HPLC has been used. Recoveries of drugs from meconium can be low (30–50%), which means that selection of proper internal standards is important. Fortunately, deuterated internal standards for most of drugs of abuse are now available. In ur case test may be due to prenatal exposure of cocaine. Chances of false positive in this case is less. For recent intake u can try cocaine level in hair. thanks