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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Is The Right Dose Of Methycobal Injection ?

Goodafternoon sir-My question is -my aged 47 years.He was prescribed Methycobal injection 500 mg inj.alternet day for 10 day.after test dose. can he take 500 mg at this age and i doubt whether doctor precibed for 500 mg instead 500 mcg. What will happen if test dose is not given? please clarify sir.
Mon, 1 Sep 2014
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General & Family Physician,  's  Response
Hello
Methylcobalamin or cyanocobalamin or mecobalamin are one and same thing i.e Vitamin B 12 .
The normal dose varies from patient to patient and disease to disease .
As for example : peripheral neuropathy 500 mcg daily I/M or I/V or 3 times in a week ( on alternate day ).
Maintenance dose:After about 2 months therapy , reduce dose to single admin of 500 mcg ( microgram ) every 1-3 month.
It is mcg NOT mg.
Test dose is given ,if patient is sensitive or not sensitive to any drug ( anaphylaxis reaction ).
If sensitive it is contraindicated . If reaction occurs patient may develop rash , anaphylaxis, bronchospasm , itching swelling .
Hope this will help you.
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What Is The Right Dose Of Methycobal Injection ?

Hello Methylcobalamin or cyanocobalamin or mecobalamin are one and same thing i.e Vitamin B 12 . The normal dose varies from patient to patient and disease to disease . As for example : peripheral neuropathy 500 mcg daily I/M or I/V or 3 times in a week ( on alternate day ). Maintenance dose:After about 2 months therapy , reduce dose to single admin of 500 mcg ( microgram ) every 1-3 month. It is mcg NOT mg. Test dose is given ,if patient is sensitive or not sensitive to any drug ( anaphylaxis reaction ). If sensitive it is contraindicated . If reaction occurs patient may develop rash , anaphylaxis, bronchospasm , itching swelling . Hope this will help you.