Hi, I am so sorry for your grand daughter but i always say early diagnosis and prevention always the best for such cases. Some say it have no cure but nowadays development of many researches that says maintaining a healthy lifestyle by exercising and avoiding smoking can help prevent fractures. Treatment may include care of broken bones, pain medication, physical therapy, braces or wheelchairs, and surgery. A type of surgery that puts metal rods through long bones may be done to strengthen them. Tentative evidence supports the use of medications of the bisphosphonate type. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Ahmed Aly Hassan