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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Prognosis Is Recommended For Elevated AST And ALT Post Chemotherapy?

Hi. I am a 35 yr old female. I don t drink alcohol and I am active. I m not overweight. I have however been diagnosed with scleroderma and lupus. My doctors started me on chemotherapy and that has helped tremendously with my autoimmune diseases however I got back my most recent blood work back and my ALT is 220 and AST is 96. I stopped the chemotherapy immediately but should I be concerned? Will the liver repair itself? Is there anything I can do to help?
Fri, 12 Jul 2019
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General Surgeon,  's  Response
Hello,

Liver enzymes may be raised because of various causes. In your case, some may be more possible but in every case, it requires evaluation of the cause. Most common causes of such liver derangement's are Alcohol, Viral hepatitis, Non-alcoholic fatty liver disease, Drugs.

Gamma GT is most commonly raised due to alcohol intake and in case you take alcohol, you need to keep control over it.

If you don't take it, you need the following tests: hepatitis virus markers, Ultrasound Abdomen, and HIDA scan. A lot many times, liver dysfunction is due to Non-Alcoholic Fatty Liver Disease (NAFLD).

So, if you have any evidence of fatty liver in Ultrasound and your other tests are negative, this rise is liver enzyme would be attributed to NAFLD. For this, you need to reduce your weight, reduce fat in diet. Stay Healthy.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Ivan R. Rommstein, General Surgeon
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What Prognosis Is Recommended For Elevated AST And ALT Post Chemotherapy?

Hello, Liver enzymes may be raised because of various causes. In your case, some may be more possible but in every case, it requires evaluation of the cause. Most common causes of such liver derangement s are Alcohol, Viral hepatitis, Non-alcoholic fatty liver disease, Drugs. Gamma GT is most commonly raised due to alcohol intake and in case you take alcohol, you need to keep control over it. If you don t take it, you need the following tests: hepatitis virus markers, Ultrasound Abdomen, and HIDA scan. A lot many times, liver dysfunction is due to Non-Alcoholic Fatty Liver Disease (NAFLD). So, if you have any evidence of fatty liver in Ultrasound and your other tests are negative, this rise is liver enzyme would be attributed to NAFLD. For this, you need to reduce your weight, reduce fat in diet. Stay Healthy. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr Ivan R. Rommstein, General Surgeon