I have been told ,this medication is causing my kidneys to shut down,I have took it for 20 to 25 years,I have so much pain now that they have taken me off this med.they we suppose to be taken 3 times a day I only took 1 per day,and it helped even my sinuses, I have been so sick since I don t take them anymore,I can t understand what was the reason to take them if I could just stop.