Hi. Thanks for your query. Noted the history of a long night of drinking in celebration, had blood in the stool in a large quantity for the second time and wants to know the reasons and whether to worry or not... As per the history you have provided., there is no pain during passing bowel movements, this means the cause can be Hemorrhoid that is piles or can be a cancer or colitis that got reactivated due to alcohol. I would advise you the following: Consult a General Surgeon to get a clinical evaluation, examination, per-rectal digital palpation, ano-proctoscopy and so on. This will give the proper diagnosis and if the polyp or hemorrhoids are large, the bleeding can recur anytime, hence the need of surgery. Also take care of the diet you take, Mild laxative to keep stools soft.