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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Why Is Enema And Carafate Prescribed And Its Side Effects?

My friend has been asked to take an enema twice a day for 1 month with Carafate. He does not have a computer, and has ask me to look this up to see the effects of this procedure. Very expensive. He was bleeding in the rectume (sp) and had it cortirized (sp) today. Can you give me any information on this procedure and the effects, etc. Thanks
Tue, 9 Sep 2014
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Internal Medicine Specialist,  's  Response
Hi,

Thank you for your query. I can understand your concerns.





Sucralfate ( Carafate) is a cytoprotective agent.It attaches to proteins on the surface of ulcers, such as albumin and fibrinogen, to form stable insoluble complexes. These complexes serve as protective barriers at the ulcer surface, preventing further damage from acid, pepsin, and bile.
It can be used in Proctitis (inflammation of rectum) from radiation or ulcerative colitis as 3 g/15 mL rectal suspension once or twice daily.
It can also be used in rectal bleeding(radiotherapy-induced ulceration) .Grade 1 bleeding experienced immediate relief with sucrasulfate enema for 1 month.
No side effects are seen.
Regards

Dr. T.K. Biswas M.D.
Mumbai
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Why Is Enema And Carafate Prescribed And Its Side Effects?

Hi, Thank you for your query. I can understand your concerns. Sucralfate ( Carafate) is a cytoprotective agent.It attaches to proteins on the surface of ulcers, such as albumin and fibrinogen, to form stable insoluble complexes. These complexes serve as protective barriers at the ulcer surface, preventing further damage from acid, pepsin, and bile. It can be used in Proctitis (inflammation of rectum) from radiation or ulcerative colitis as 3 g/15 mL rectal suspension once or twice daily. It can also be used in rectal bleeding(radiotherapy-induced ulceration) .Grade 1 bleeding experienced immediate relief with sucrasulfate enema for 1 month. No side effects are seen. Regards Dr. T.K. Biswas M.D. Mumbai