Hi,I am Dr. Amitkumar Sharma (Internal Medicine Specialist). I will be looking into your question and guiding you through the process. Please write your question below.
My father had been taking 20 mg of Lisinopril for hypertension for years. In December his doctor upped the prescription to 40 mg and added Losartan. Since then he has been experiencing an extreme paranoia and some depression. Is it possible that this is being caused by the blood pressure medication?
hi, The drug lisinopril belongs to the class ACE inhibitors. studies have implicated them in causation of depression. You can view the article: (Psychiatry- Dec 2008; 5(12): 28–41;General Medical Drugs Associated with Depression). Also, recent evidence suggested 'against' the use of losartan combined with ace inhibitors. In either case, you need to get a change over of prescription, as there are many other alternatives like ca blockers and diuretics. Consult your doctor again. hope this helped.
I find this answer helpful
You found this answer helpful
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..
Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer.
For a more detailed, immediate answer, try our premium service
[Sample answer]
We use cookies in order to offer you most relevant experience and using this website you acknowledge that you have already read and understood our
Privacy Policy
Will Blood Pressure Medication Cause Depression?
hi, The drug lisinopril belongs to the class ACE inhibitors. studies have implicated them in causation of depression. You can view the article: (Psychiatry- Dec 2008; 5(12): 28–41;General Medical Drugs Associated with Depression). Also, recent evidence suggested against the use of losartan combined with ace inhibitors. In either case, you need to get a change over of prescription, as there are many other alternatives like ca blockers and diuretics. Consult your doctor again. hope this helped.