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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Will Primolut Injections Cause Any Side Effects During Pregnancy?

just wanna know lil abt primolut depot inection on pregnat woman? coz my wife lost her pregnancy at week 24 and now she pregnant again and in 16 weeks now she saw lil blood yesterday and the doctor put her on 6 primolut injection, so my concern now is the side effect that is gonna have on the mother and the baby



Fri, 17 Jan 2014
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OBGYN 's  Response
Hi,
Thanks for the query.
Progesterone injections help in preventing premature uterine contractions.
And thereby prevent abortions and preterm deliveries to some extent.
Primulot belongs to category D drugs in pregnancy.
According to studies it may lead to some adverse effects.
Though there are no much evidences in regular practice, better to be careful.
Using natural micronized progesterone is a better alternative.
Natural micronized progesterone belongs to category B drug.
This is may not harm the baby according to animal studies.
So, discuss this things with your doctor and follow her advice.
Along with this, taking bed rest and restricting physical activity is recommended.
Take care.

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OBGYN Dr. Shanti Vennam's  Response
Hello,
Primolut is not recommended in pregnancy. If there is bleeding at 16 weeks of pregnancy, hormonal deficiency as a cause is less likely and other causes like trauma, placental insufficiency, infection etc., should be looked in to. Please consult a specialist in high risk pregnancy at once and get a proper advise and assessment. Meanwhile ask her to take absolute bed rest, avoid all strenuous activity including intercourse. A sonogram should be helpful. Hope you find this information useful. Take care.
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Will Primolut Injections Cause Any Side Effects During Pregnancy?

Hi, Thanks for the query. Progesterone injections help in preventing premature uterine contractions. And thereby prevent abortions and preterm deliveries to some extent. Primulot belongs to category D drugs in pregnancy. According to studies it may lead to some adverse effects. Though there are no much evidences in regular practice, better to be careful. Using natural micronized progesterone is a better alternative. Natural micronized progesterone belongs to category B drug. This is may not harm the baby according to animal studies. So, discuss this things with your doctor and follow her advice. Along with this, taking bed rest and restricting physical activity is recommended. Take care.