Zollinger-ellison syndrome
What is Zollinger-ellison syndrome?
Zollinger–Ellison Syndrome (ZES) is caused by a non–beta islet cell (islet of Langerhans), gastrin-secreting tumor of the pancreas that stimulates the acid-secreting cells of the stomach (parietal cells) to maximal activity, with consequent gastrointestinal mucosal ulceration. ZES may occur sporadically or as part of an autosomal dominant familial syndrome called multiple endocrine neoplasia type 1 (MEN 1). The primary tumor is usually located in the pancreas, duodenum or abdominal lymph nodes, but ectopic locations have also been described (e.g., heart, ovary, gallbladder, liver, kidney).
Questions and answers on "Zollinger-ellison syndrome"
Recent questions on Zollinger-ellison syndrome
Related Disease & Conditions
Related Drugs/Medications
Related Treatment/Therapy
Related Lab Tests
Related Procedures
Related Medical Topics