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What is Schistocyte?
A schistocyte or schizocyte (from Greek schistos for "divided" or schistein for "to split", and kytos for "hollow" or "cell") is a fragmented part of a red blood cell. Schistocytes are typically irregularly shaped, jagged, and have two pointed ends. A true schistocyte does not have central pallor. Schistocytes are sometimes referred to as "helmet cells".
Several microangiopathic diseases, including disseminated intravascular coagulation and thrombotic microangiopathies, generate fibrin strands that sever red blood cells as they try to move past a thrombus, creating schistocytes.
Schistocytes are often seen in patients with hemolytic anemia. They are frequently a consequence of mechanical artificial heart valves and hemolytic uremic syndrome, thrombotic thrombocytopenic purpura, among other causes.
Excessive schistocytes present in blood can be a sign of microangiopathic hemolytic anemia (MAHA) where the most common cause is aortic stenosis.
Questions and answers on "Schistocyte"
the peripheral blood smear shows marked anisopoikilocytosis, microcytic, hypochromic RBC with normocytic target cells and schistocytes seen. WBC...
MD You might be suffering from hypochromic microcytic anemia. It may be due to iron deficiency most commanly. May be due to thallasemia minor....
Hi, my 12 year old daughter's blood report says - 'SHOW MILD ANISOPOIKILOCYTOSIS, MAJORITY ARE MICROCYTIC HYPOCHROMIC CELLS WITH OCCASIONAL...
MD Hello,
The blood smear report does, in fact, suggest that she would be best tested for THALASSEMIA.
Hope I have answered your query. Let me know if...
hi, good day doc! my lab result of my son 8yrs old his peripheral bld smear result is smear show hypochromic rbc w/ anisopoikilocytosi in the form...
MD May it is due to iron deficiency.but you should perform a osmotic fragility test, coomb test and a Hb electrophoresis.
