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Are There Any Interactions Between Warfarin, L-Theanine And Choline?

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Posted on Thu, 27 Oct 2016
Question: This will take a little time to type OK? I am currently taking medications of Metoprolol, Diltiazem, Warfarin and Pravastatin for Atrial Fibrilation. Will dietary supplements of L-theanine 150 mg, Choline 150 mg, Phenylpiracetam 50 mg Noopept 15 mg daily affect any of my medications?
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Answered by Dr. Ilir Sharka (1 hour later)
Brief Answer:
I would explain as follows:

Detailed Answer:
Hello!

Thank you for asking on HCM!

Regarding your concern, I would explain that the main interactions in your current therapy are:

a-Between warfarin adn L- theanin. Green tea decreases effects of warfarin by pharmacodynamic antagonism. So it may decrease the effects of warfarin.

b-While warfarin and choline both increase anticoagulation. So, choline can increase the effects of warfarin, by increasing your risk of bleeding.

So, they should be used with caution, by a close monitoring of INR. Combination may decrease warfarin efficacy.

There are no significant interactions between these supplements and diltiazem or metoprolol.

Hope to have been helpful!

Kind regards,

Dr. Iliri


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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Ilir Sharka

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Practicing since :2001

Answered : 9533 Questions

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Are There Any Interactions Between Warfarin, L-Theanine And Choline?

Brief Answer: I would explain as follows: Detailed Answer: Hello! Thank you for asking on HCM! Regarding your concern, I would explain that the main interactions in your current therapy are: a-Between warfarin adn L- theanin. Green tea decreases effects of warfarin by pharmacodynamic antagonism. So it may decrease the effects of warfarin. b-While warfarin and choline both increase anticoagulation. So, choline can increase the effects of warfarin, by increasing your risk of bleeding. So, they should be used with caution, by a close monitoring of INR. Combination may decrease warfarin efficacy. There are no significant interactions between these supplements and diltiazem or metoprolol. Hope to have been helpful! Kind regards, Dr. Iliri