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Can Dexamethasone, Methotrexate And Naproxen Be Taken Together?

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Posted on Sat, 23 May 2015
Question: can you take a small dose of Dexamethasone with Methotrexate and Naproxen?
doctor
Answered by Dr. Dr. Muhammad Sareer Khalil (18 minutes later)
Brief Answer:
Need more information

Detailed Answer:
Hello and Welcome

I appreciate your concern

If appropriate, Kindly answer the following to help you better

Please state the exact dose of Methotrexate and Naproxen that you are currently taking.
For what condition are you using both these medication?
Do you have a history of Rheumatoid arthritis ?
Do you have a history of any malignancy ?
Have you had your renal function tests done recently, if so kindly share the results
For how long have you been taking Methotrexate and Naproxen, Please specify the time period.

Wishing you best of health

Thanks
Above answer was peer-reviewed by : Dr. Raju A.T
doctor
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Follow up: Dr. Dr. Muhammad Sareer Khalil (1 hour later)
I have Rheumatoid arthritis, I take 10 2.5MG of Methotrexate for a year.
and 1 5MG tablet a day for a year.

thanks!
doctor
Answered by Dr. Dr. Muhammad Sareer Khalil (6 hours later)
Brief Answer:
Yes, dexamethasone can be added, in consult with your doctor

Detailed Answer:
Hello again,

Methotrexate is started in Rheumatoid arthritis patients when there is severe and active disease with poor response to full dose of NSAIDs like naproxen.

The next logical step is to XXXXXXX out the dose of Methotrexate with a single oral dose not to exceed 20 mg /week, to minimize the risk of bone marrow suppression.

Dexamethasone is useful in providing rapid control and relief in inflammation and RA disease flares. It can be used for a short course and then tapered. Abrupt discontinuation can lead to complications. For more aggressive disease , it can be administered for longer periods of time, starting at a higher dose to cover the flare response and continuing it at a minimum maintenance dose, in consult with your doctor/Rheumatologist.

Let me know if you have any query.

Thanks.

Please consult your doctor before deciding on any further course of action.

Dr. M.S. Khalil

Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Yogesh D
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Answered by
Dr.
Dr. Dr. Muhammad Sareer Khalil

General & Family Physician

Practicing since :2012

Answered : 2906 Questions

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Can Dexamethasone, Methotrexate And Naproxen Be Taken Together?

Brief Answer: Need more information Detailed Answer: Hello and Welcome I appreciate your concern If appropriate, Kindly answer the following to help you better Please state the exact dose of Methotrexate and Naproxen that you are currently taking. For what condition are you using both these medication? Do you have a history of Rheumatoid arthritis ? Do you have a history of any malignancy ? Have you had your renal function tests done recently, if so kindly share the results For how long have you been taking Methotrexate and Naproxen, Please specify the time period. Wishing you best of health Thanks