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Can Doxepin Be Taken With Depakote, Lamictal, Zoloft And Rexulti?

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Posted on Tue, 15 May 2018
Question: hello, can you take doxapin with depakote of Zoloft Lamictal and of rexulti? thank you
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Answered by Dr. Michelle Gibson James (34 minutes later)
Brief Answer:
some interactions can occur

Detailed Answer:
Hi, thanks for using healthcare magic

There are some interactions that would require monitoring but they can be used together.

The interactions are--(1) lamotrigine (lamictal) increases the toxicity of sertraline (zoloft)
(2)sertraline (zoloft) may increase the effect and level of brexiprazole (rexulti)
by affecting its break down
(3) Depakote increases lamotrigine (lamictal) by decreasing its breakdown

It is possible that you may not experience any side effects of these reactions but you should be monitored to see if any occurs

I hope this helps, feel free to ask any other questions
Note: For further guidance on mental health, Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Michelle Gibson James

General & Family Physician

Practicing since :2001

Answered : 16808 Questions

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Can Doxepin Be Taken With Depakote, Lamictal, Zoloft And Rexulti?

Brief Answer: some interactions can occur Detailed Answer: Hi, thanks for using healthcare magic There are some interactions that would require monitoring but they can be used together. The interactions are--(1) lamotrigine (lamictal) increases the toxicity of sertraline (zoloft) (2)sertraline (zoloft) may increase the effect and level of brexiprazole (rexulti) by affecting its break down (3) Depakote increases lamotrigine (lamictal) by decreasing its breakdown It is possible that you may not experience any side effects of these reactions but you should be monitored to see if any occurs I hope this helps, feel free to ask any other questions