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Can Lupron Alter Liver Enzyme Levels?
Question: Hello, Can Lupron injections affect my liver enzimes. 1.5x ast and 2.7x of normal high end range. I have prostate cancer. thank you XXXXXXX Kay 2.7x alt
Brief Answer:
it is possible
Detailed Answer:
Hello,
it is possible as there are some are reports about hepatitis and other types of liver dysfunction with this drug but other potential causes should have to be excluded first. In patients like you I usually start with an ultrasound scan of the liver and adjacent tissues (gallbladder and pancreas). The patient's history may provide clues to guide the rest of the investigation.
For example, a patient with a history of chronic hepatitis may have to be tested for a recurrence of hepatitis. Prostate cancer may invade the liver, so radiological tests are indicated.
I hope you find my comments helpful!
Kind Regards!
it is possible
Detailed Answer:
Hello,
it is possible as there are some are reports about hepatitis and other types of liver dysfunction with this drug but other potential causes should have to be excluded first. In patients like you I usually start with an ultrasound scan of the liver and adjacent tissues (gallbladder and pancreas). The patient's history may provide clues to guide the rest of the investigation.
For example, a patient with a history of chronic hepatitis may have to be tested for a recurrence of hepatitis. Prostate cancer may invade the liver, so radiological tests are indicated.
I hope you find my comments helpful!
Kind Regards!
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
hello, in my younger days I used to drink much more than I do now. Before dinner on the weekends now, I have maybe two glasses of beer . I have been doing this for years now. I watch my enzynes alt and ast every time I have a blood test. I have been watching this for the last 30 years. I have copies of these tests. Never has it been this high , always within the range. Now it is ast 67 and 112 alt. I did have a sereous tooth extraction a month ago . Dr gave me two weeks penicilen and I used a lot of tylonal. Could that spike my ast and alt? How high are those numbers. My psa is very good now .04. Could the combination Lupron,tylinal,peniclan and beer do this to my liver?
Brief Answer:
it is possible too...
Detailed Answer:
When the liver enzymes increase, the first thing to check is potential toxicity due to drugs or alcohol. You hadn't mentioned alcohol in your first text, so I didn't comment on it. A simple way to see whether your drinking is too much for your liver is the gamma-GT enzyme. This is notoriously high in individuals who drink alcohol regularly.
The transaminases are considered to be significantly high when the exceed three times the upper normal levels. For example if the lad considers an ALT to be normal up to 40 U/L then a significantly high ALT should be higher than 120 U/L. Lower elevations do not exclude serious disorders though, so investigation is required anyway.
Getting back to your new question, all hepatotoxic substances may cause injury to the liver particularly when combined. You can't tell which of them (if any) is the real cause. Investigation should exclude other causes before attributing anything to drugs or other toxins.
Kind Regards!
it is possible too...
Detailed Answer:
When the liver enzymes increase, the first thing to check is potential toxicity due to drugs or alcohol. You hadn't mentioned alcohol in your first text, so I didn't comment on it. A simple way to see whether your drinking is too much for your liver is the gamma-GT enzyme. This is notoriously high in individuals who drink alcohol regularly.
The transaminases are considered to be significantly high when the exceed three times the upper normal levels. For example if the lad considers an ALT to be normal up to 40 U/L then a significantly high ALT should be higher than 120 U/L. Lower elevations do not exclude serious disorders though, so investigation is required anyway.
Getting back to your new question, all hepatotoxic substances may cause injury to the liver particularly when combined. You can't tell which of them (if any) is the real cause. Investigation should exclude other causes before attributing anything to drugs or other toxins.
Kind Regards!
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
did you get my question I sent to you 10 mins ago?
Brief Answer:
I didn't...
Detailed Answer:
No, I only see one question 22 hours ago and the last question (1min ago)...
I didn't...
Detailed Answer:
No, I only see one question 22 hours ago and the last question (1min ago)...
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Hello, My dr. told me to stop drinking for 3 weeks and than take another test. Is 3 weeks long enough to see if alcohol is the problem? If it goes higher what is your recommendation ? If it stays the same then what? If it goes down then what? My dr. says I'm in pretty good shape except foe these problems. I'm 6 -1 .190lbs , bp 135 over 78. I work out every day 30 to 40mins. I play tennis mostly on the weekends. Thank You XXXXXXX Kay
Brief Answer:
it should be enough
Detailed Answer:
Hello,
tests like gamma GT require 4 weeks for reversal of elevations but 3 weeks should suffice at least to get a good idea of what's going on. If the values go down then alcohol would have to be blamed and follow-up testing a month later would confirm it. If the values stay the same then alcohol can be excluded as a potential cause, although continuing consumption would not be recommended thereafter. If the values rise then it's probably something that evolves, which would require further testing (with hepatitis antibodies, antinuclear antibodies, etc).
Kind Regards!
it should be enough
Detailed Answer:
Hello,
tests like gamma GT require 4 weeks for reversal of elevations but 3 weeks should suffice at least to get a good idea of what's going on. If the values go down then alcohol would have to be blamed and follow-up testing a month later would confirm it. If the values stay the same then alcohol can be excluded as a potential cause, although continuing consumption would not be recommended thereafter. If the values rise then it's probably something that evolves, which would require further testing (with hepatitis antibodies, antinuclear antibodies, etc).
Kind Regards!
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
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