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Can Morphine Injection Cause Psychotic Reactions?

Posted on Thu, 4 Dec 2014

Question: I HAD MORPHINE INJECTION 10MGMS PLUS OXYCONTIN x3 AND PREDNISOLONE 60MGMS IN A 12 HOUR PERIOD AND WENT COMPLETELY BESERK. i BECAME SUICIDAL , FELL OUT OF BED. PULLED A CATHETER OUT AND WAS FOUND ON THE FLOOR TALKING TO A NURSES BELL AND ALSO TALKING TO MYSELF. THE DR CONTINUED TO GIVE ME MORPHINE OVER THE NEXT 3 DAYS AND i BECAME EXTREMELY ABUSIVE, SWEARING AND GENERALLY OUT OF MY MIND. iS THIS THE USUAL RACTION TO MORPHINE.? THE Dr WAS TOLD i WAS ALLERGIC TO MORPHINE AND I HAD A RED ]ALEERT BAND ON.

Answered by Dr. Prakash H Muddegowda (47 minutes later)

Brief Answer:
Its very unusual reaction, but seen.

Detailed Answer:
Hi,
Thanks for asking.

I am Dr. Prakash HM and I will be answering your query.

Based on your query, my opinion is as follows:

1. Morphine is not commonly known to cause psychotic symptoms.
2. Its rather unusual, but hallucinations, agitation are rarely seen.
3. However, more commonly oxycontin and rarely prednisone - steroid induced psychosis.. Both can cause psychosis.

Now that you had a allergic reaction, stay away from morphine and any derivatives and always remember to point out to everyone.

Hope you are well now.

Any further queries, happy to help again.

Dr. Prakash HM

Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Ashwin Bhandari