Can Synprotik Be Taken For Chronic Kidney Disease?

Posted on Thu, 7 Jan 2016

Question: MY doctor has prescribed as follows metpurexl 1-0-1, minipress xl 5 1-0-1, Lnbloc1-0-1, stator 0-0-1, renomega 0-1-0-, reneplus Fe 0-1-0, renelog 1-1-1, calcitab 1-0-1, Twichek0-0-1, synprotik 1-0-1 [ here morning-noon-night to be understood as mentioned above. My queries are as below
1] I could not find any info about synprotik on internet that for CKD4 patient, can you please explain?
2] Why reneplus Fe is prescribed when the info on net does not show any effect related to kidney?
3] why renomega is that just because of name beginning with reno?
Oh, I forgot to tell you that my creatinine is 2.1 blood urea is 80, haemoglobin 9.0 serum electrolite balance is ok as per the report rest alll normal.

Answered by Dr. Rakesh Madhyastha (8 hours later)

Brief Answer:
Need more info

Detailed Answer:
Hello

Thanks for the query

I understand you are suffering from chronic kidney disease however I need a few more details in order to help you as the drugs are given for specific renal diseases

1. since how long have you had chronic kidney disease ?
2. was a biopsy done at any point of time? what was the result ?
3. was serum iron study done? please furnish the report
4. what is the size of your kidneys on ultrasound ?

Please get back to me, I am awaiting your reply

Regards

Above answer was peer-reviewed by : Dr. Prasad

Follow up: Dr. Rakesh Madhyastha (2 hours later)

medication is for 16 months
no biopsy done
no
left kidney is small 7.4 x 3.8
right kidney 9 x 3.8

Answered by Dr. Rakesh Madhyastha (18 hours later)

Brief Answer:
Medications explained

Detailed Answer:
Hello , Welcome to HCM.

Thanks for getting back, I am sorry for the short delay in my reply.

1. You are on Reneplus Fe because your hemoglobin is low. We would want the Hb to be about 12 in a chronic kidney disease patient. I recommend that you get serum iron studies done and be on erythropoetin as well

2. Synprotik is not a drug used for chronic kidney disease. It is a probiotic usually given for people with loose stools or irritable bowel. It has no indication for CKD unless the patients are suffering from it

3. Renomega contains omega 3 fatty acids, studies have shown that these fatty acids help in retarding the progress of kidney disease. It also helps boost immunity .

I hope I was of help, if you have any further queries please get back to me

Regards

Above answer was peer-reviewed by : Dr. Arnab Banerjee

Follow up: Dr. Rakesh Madhyastha (4 hours later)

Erythropoitin was given before some six months when the haemoglobin level increased by two but again in a month it came down and now its at the same level in a range of [+/- 0.2] for last six months.

It seems that for a short period only haemoglobin increases using erythropoitin the standard dose was 10,000 IU [ three times with a frequency of 10 days]

Initially when for the first time we went to doc the haemoglobin was 10 and the blood ureas as well as serum creatinine levels were just crossing the boundaries of the limit when medication was started. Later it never reached and remained steady at those levels. Blood urea and creatinine started increasing after taking doses initially for a period of two months. GFR calculated was around 27$ at that time.[ using DTPA Renal test]

Now my question is when the same prescription is repeated with minor changes such as adding one or two drugs/ suppliments more for last 16 months.has created this problem or how?

When a high potency drug given to the patients increases the intensity of the symptoms [ induction]and then the doctors advise low potency doses to bring the patient to normal .What is your opinion about this Was I treated in this way? This I am quoting as I am involved in animal toxicity testing of drugs.
Being a post grad of 74 batch in Microbiology I am refering to this out of my experience.
pl respond

Answered by Dr. Rakesh Madhyastha (6 hours later)

Brief Answer:
Need more clarity

Detailed Answer:
Hello

Thanks for getting back, I am not sure I understand your question.

1. Which prescription with minor changes are you talking about? What were the drugs that were changed?
2. What drug was used as 'induction'? and which drug was used in low potency?

Erythropoietin is very essential for a patient with CKD, it is because erythropoietin is not produced in the kidney of CKD patients. Epo helps in stimulating the bone marrow to produce blood

I hope I was of help, if you have any further queries please get back to me

Regards

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Above answer was peer-reviewed by : Dr. Vinay Bhardwaj