Can Synthroid Be Taken At Night Rather Than Mornings?

Posted on Mon, 2 May 2016

Question: I would like to start taking my 125mcg of generic synthroid at night rather than in the mornings. I took the synthroid today around 11 AM. Can I take it again tonight to start switching the time of day I take this? How switch the time of day I take this?

Answered by Dr. Shehzad Topiwala (2 hours later)

Brief Answer:
Synthroid

Detailed Answer:
Take it from tomorrow night onwards because taking an extra one tonight in addition to a morning dose would effectively double the dose for today.

Now please note that synthroid or its generic are best taken 60 minutes before breakfast, with water. This means before any food or beverage or other medication, particularly iron or calcium supplements.
This is to ensure adequate absorption from the gut.

I understand you wish to switch to night time. This can be done provided at least 3 hours have passed since your last meal of the night ie dinner and you are not going to be eating anything else after that till bedtime. If you can observe this, then you can take synthroid with water at bedtime, when it has been 3 hours or more since last meal.
This also is to make sure it is absorbed well

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar