Question: I have been taking Letrozole as a follow up to a mastectomy for carcinoma in situ. There was no metastasis. It is beginning to cause a lot of bursitis all over. It has been in my knees, ankles, hips, and now it is appearing in my jaw. It also makes me very tired, I can't remember things and the hot flashes are awful. I'm taking Estroven to help with some of the symptoms, and it does help a little bit. The immobility, however, is really a problem. I've been trying to manage with joint injections, etc., but it's getting ahead of me. I am a very active 77 years of age--I am on a leadership team for a religious community. I am wondering if Tamoxifen would have less side effects and give me more mobility again. If you think it would, I will ask my oncologist to change. She has told me that is an option. Thank you for any help you can give me.

Thank you for your answer. I appreciate the help.

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