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Can Spironolactone Cause Low Sperm Count?

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Posted on Tue, 29 Apr 2014
Question: can spironolactone cause low sperm count, I have recently been trying to father a child and couldn't get my partner pregnant, so I have had semen analysis done and I have a very low sperm count(6% motility).the doctor suggest, it might due to the spironolactone I am on.
doctor
Answered by Dr. Mahesh Koregol (33 minutes later)
Brief Answer: Yes Detailed Answer: Hi You are right. Spironolactone does cause reduced sperm count and motility. Please visit the doctor who prescribed this drug and ask if it can be modified. If not only option left is to undergo ICSI (Intracytoplasmic sperm injection) technique which introduces sperms into egg. Its an extension of IVF Procedure. Let me know if you have any more questions. Regards Dr. Mahesh Koregol
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Mahesh Koregol (14 minutes later)
Thank you for your reply, if the doctor said I should stop taking it.like how long after stopping it, will my sperm count increases.and is the damage done not permanent as I have been on the drug for nearly 3 years now.
doctor
Answered by Dr. Mahesh Koregol (10 hours later)
Brief Answer: 3 months Detailed Answer: Hi You can get tested again after 3 months of stopping the drug. Also stop alcohol and smoking if you have habit. Follow balanced diet and exercise. Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Mahesh Koregol

Infertility Specialist

Practicing since :2000

Answered : 3836 Questions

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Can Spironolactone Cause Low Sperm Count?

Brief Answer: Yes Detailed Answer: Hi You are right. Spironolactone does cause reduced sperm count and motility. Please visit the doctor who prescribed this drug and ask if it can be modified. If not only option left is to undergo ICSI (Intracytoplasmic sperm injection) technique which introduces sperms into egg. Its an extension of IVF Procedure. Let me know if you have any more questions. Regards Dr. Mahesh Koregol