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Child Has Hemolytic Anemia Since Birth. Done Spenectomy. What Could Be The Reason For Low Hemoglobin?

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Posted on Mon, 24 Sep 2012
Question: Hello,

My son XXXXXXX XXXXXXX age 7 years is suffereing from hemolytic anemia since birth. His hemoglobin remains at 8 to 9 g/dL and sometimes require blood transfusion as well. We had shown him in highly reputed hospitals Like AIIMS, Sir XXXXXXX XXXXXXX Hospital and also in CMC Vellore , however, nothing is diaognised till date in last 7 years. Last year we had gone ahead with Spenectomy operation in Sir XXXXXXX XXXXXXX hospital and thereafter his Hemoglobin is stable at 10 g/dL and in last one year no requirement of blood transfusion as well. However, doctors have prescrived lifelong tabs to fight any infection ( Pencillin 200mg twice daily ). Pls suggest what could be the reason of low hemoglobin and how can it be improved to level of 13g/dL.
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Answered by Dr. Ioan Dorian OANA (2 hours later)
Hi XXXXXXX

Thanks for your query.

Please double check if you did not miss some details, maybe an additional diagnosis. Why I am saying this? Penicillin can cause immune hemolysis and this is why normally penicillin should be discontinued in patients who develop hemolysis.

I suspect that we speak about autoimmune hemolytic anemia, because you had gone ahead with splenectomy operation, but then I understand even less why the doctors have prescribed lifelong Penicillin.

Please send me much more details, all medical reports you have and I am looking forward to try helping you more.

If you have any more queries, feel free to ask.

Regards
Dr. Dorian Oana MD, PhD
Note: For further queries related to your child health, Talk to a Pediatrician. Click here to Book a Consultation.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Ioan Dorian OANA

Oncologist

Practicing since :2006

Answered : 101 Questions

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Child Has Hemolytic Anemia Since Birth. Done Spenectomy. What Could Be The Reason For Low Hemoglobin?

Hi XXXXXXX

Thanks for your query.

Please double check if you did not miss some details, maybe an additional diagnosis. Why I am saying this? Penicillin can cause immune hemolysis and this is why normally penicillin should be discontinued in patients who develop hemolysis.

I suspect that we speak about autoimmune hemolytic anemia, because you had gone ahead with splenectomy operation, but then I understand even less why the doctors have prescribed lifelong Penicillin.

Please send me much more details, all medical reports you have and I am looking forward to try helping you more.

If you have any more queries, feel free to ask.

Regards
Dr. Dorian Oana MD, PhD