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Does Diltiazem Interact With Lisinopril And Pravastatin?

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Posted on Thu, 27 Apr 2017
Question: I started taking Diltiazem 120 mg one per day about six months ago. I am experiencing a problem with urination and bowel movement. I have a frequent need to urinate with little output and the bowel movement is choppy and not full. I also take Lisinopril 20 mg one per day and Pravastatin Sodium 40 mg one per day.
I did not have the bladder - bowel problem until I started taking the Diltiazem or so it seems. Could the Diltiazem be the cause? I am male 64 years of age very active run 3 miles a day 5 times a week. I have A-fib and the Diltiazem is to help with heart rate and blood pressure.
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Answered by Dr. Ilir Sharka (32 minutes later)
Brief Answer:
My advice as follows:

Detailed Answer:
Hello!

Welcome on HCM!

Regarding your concern, I would explain that troubles with urination are not a known adverse effect related to Diltiazem. While troubles with bowel movements (diarrhea or constipation) have been reported as an adverse effect of this drug in up to 4 % of the persons.

Anyway, I would recommend performing some tests to investigate for other possible causes that may cause your troubles:

- an abdominal ultrasound to examine your urinary tract (including the prostate)
- kidney and liver function tests
- fasting glucose
- blood electrolytes for possible electrolyte imbalance
- a urine analysis.

If all these tests result normal (other causes have been excluded) you should discuss with your doctor on the possibility of switching from diltiazem to another drug which you may tolerate better.

Hope to have been helpful!

Kind regards,

Dr. Iliri
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Ilir Sharka

Cardiologist

Practicing since :2001

Answered : 9544 Questions

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Does Diltiazem Interact With Lisinopril And Pravastatin?

Brief Answer: My advice as follows: Detailed Answer: Hello! Welcome on HCM! Regarding your concern, I would explain that troubles with urination are not a known adverse effect related to Diltiazem. While troubles with bowel movements (diarrhea or constipation) have been reported as an adverse effect of this drug in up to 4 % of the persons. Anyway, I would recommend performing some tests to investigate for other possible causes that may cause your troubles: - an abdominal ultrasound to examine your urinary tract (including the prostate) - kidney and liver function tests - fasting glucose - blood electrolytes for possible electrolyte imbalance - a urine analysis. If all these tests result normal (other causes have been excluded) you should discuss with your doctor on the possibility of switching from diltiazem to another drug which you may tolerate better. Hope to have been helpful! Kind regards, Dr. Iliri