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Does Hydrochlorothiazide Interact With Lisinopril?
Question: MY DR PRSCRIBED ME HYDROCLOROT WITH MY LISINOPRIL I FEEL IT IS EFFECTING MY BODY AT NIGHT WHEN I SLEEP I FEEL I HAVE IRREGULAR HEART BEAT.iS THAT COMMON? SHE HAS ME TAKING LISINOPRIL ONE DAY 20MG THEN HYDROCLOROT WITH LISINOPRIL ANOTHER DAY ALTERNATING .WHEN I TAKE BOTH THOSE ARE THE EVEINGS I CANT SLEEP.I FEEL THIS IS DANGEROUS.WHY CANT SHE GET THIS RIGHT IM ALWAYS FEELING NOT GOOD
Brief Answer:
I would explain as follows:
Detailed Answer:
Hello!
Welcome and thank you for asking on HCM!
Regarding your concern I would explain that your symptoms do not seem to be related to your actual therapy.
This is a safe drug combination as they do not interact with each other.
I recommend consulting with your attending physician and performing further tests to investigate for the possible cause:
- a resting ECG
- complete blood count for chronic anemia
- blood electrolytes for possible imbalance
- thyroid hormone levels for possible thyroid dysfunction
An ambulatory 24-48 hours ECG monitoring would examine better you heart rhythm trends through the day and exclude possible arrhythmia.
I would recommend taking hydrochlorothyazide every morning, as it is better tolerated in the morning (considering that it acts as a diuretic).
You can take lisinopril in the morning or twice daily (depending on the dose).
You should know that there are also certain drug formulations which contain both an ACEI (like lisinopril) and hydrochlorothyazide in one tablet, as this is quite a normal antihypertensive drug combination.
Hope to have been helpful!
Kind regards,
Dr. Iliri
I would explain as follows:
Detailed Answer:
Hello!
Welcome and thank you for asking on HCM!
Regarding your concern I would explain that your symptoms do not seem to be related to your actual therapy.
This is a safe drug combination as they do not interact with each other.
I recommend consulting with your attending physician and performing further tests to investigate for the possible cause:
- a resting ECG
- complete blood count for chronic anemia
- blood electrolytes for possible imbalance
- thyroid hormone levels for possible thyroid dysfunction
An ambulatory 24-48 hours ECG monitoring would examine better you heart rhythm trends through the day and exclude possible arrhythmia.
I would recommend taking hydrochlorothyazide every morning, as it is better tolerated in the morning (considering that it acts as a diuretic).
You can take lisinopril in the morning or twice daily (depending on the dose).
You should know that there are also certain drug formulations which contain both an ACEI (like lisinopril) and hydrochlorothyazide in one tablet, as this is quite a normal antihypertensive drug combination.
Hope to have been helpful!
Kind regards,
Dr. Iliri
Note: For further queries related to coronary artery disease and prevention, click here.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
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