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Does Hydrocodon/Acetaminoph Have Any Interaction With Pantoprazole, Tamsulosin And Lisinopril?

Posted on Thu, 27 Feb 2014

Question: I am taking Hydrocodon-Acetaminoph 7.5-325 because of a knee replacement. Does this drug conflict with with any of the following drugs I also am taking. They are : Pantoprazole Sod Dr, Pravastain, Tamsulosin and Lisinopril.

Answered by Dr. Praveen (45 minutes later)

Brief Answer: No interaction.Can be continued safely Detailed Answer: Hi.Thanks for writing on XXXXXXX I am really glad to know that you have asked this question.When ever we are on such a polypill its always good to know the possible interactions. Hydrocodone/Acitaminophen does not have any interaction with the rest of the medications that have been mentioned.They can be continued safely. Hope I have clarified your query and answered satisfactorily. Thank you and Good luck.

Above answer was peer-reviewed by : Dr. Prasad

Follow up: Dr. Praveen (8 hours later)

Is it safe to take Advil with the medications I mentioned in my original request??

Answered by Dr. Praveen (4 hours later)

Brief Answer: Impairs renal function, interferes with BP control Detailed Answer: Hello. Advil is ibuprofen. It may result in renal function deterioration, particularly in elderly (or in case of dehydration). Further it may diminish blood pressure lowering effect of Lisinopril. Needs close monitoring of both Blood pressure and renal function. I were suggest only if necessary and do not advise routine use for this reason. Hope this answers your query.

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Above answer was peer-reviewed by : Dr. Vaishalee Punj