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Does Intake Of Metroprolol, Hydralazine And Finasteride Help In Treating Urinary Retention?
Question: Yes I am concerned that my husband may be having some health problems, ie worse renal insufficiency and more problems with urinary retention. The drugs I am concerned about are Hydralazine 100 mg bid, Metroprolol 25 mg once q day,and Finasterlide 5mg once q day, His renal problem went from stage 2 to stage 3. ready for answer
Brief Answer:
Explained in detail
Detailed Answer:
Hello and welcome
Your concern is appreciated
The drugs you mentioned limte hydralazine which is do have side effects like painful or diificult urination and it is also known to cause 20% of patient taking 400mg per day to develop systemic lupus erythmatosus syndrome some expert may suggest to check patients acetylator status
Renal side effects are more present in idiopathic systemic lupus erythmatosus immune complex glomerulonephritis is rare in drug induced lupus
Rarely it may cause rapidly progressing glomerulonephritis accompanied by anemia positive ANA titer and positive anti-DNA antibody titer.
Metoprolol is a selective beta 1 adrenoreceptor blocker renal side effects are not there as such although it can cause frequent mucturation concomitently given with hydralazine lead to increase concentration of metprolol
No dose adjustments are required in renal impairment
Finasterlide is steriod resuctase inhibitor
And it has definately effects on renal functions and its dose is adjusted in patient with renal insufficiency
Regarding decrease renal insufficiency other factors like old age as with age number of funtioning nephrons decreases and the enlarged prostate can cause back preasure on the urinary system and effect kidney fuction. So these all can contribute to the decrease renal functions.
Hope it helps
Thanks
wishing you best of health
let me know if you have any query
Please consult your doctor before taking any further course of action
Dr M.S Khalil
Explained in detail
Detailed Answer:
Hello and welcome
Your concern is appreciated
The drugs you mentioned limte hydralazine which is do have side effects like painful or diificult urination and it is also known to cause 20% of patient taking 400mg per day to develop systemic lupus erythmatosus syndrome some expert may suggest to check patients acetylator status
Renal side effects are more present in idiopathic systemic lupus erythmatosus immune complex glomerulonephritis is rare in drug induced lupus
Rarely it may cause rapidly progressing glomerulonephritis accompanied by anemia positive ANA titer and positive anti-DNA antibody titer.
Metoprolol is a selective beta 1 adrenoreceptor blocker renal side effects are not there as such although it can cause frequent mucturation concomitently given with hydralazine lead to increase concentration of metprolol
No dose adjustments are required in renal impairment
Finasterlide is steriod resuctase inhibitor
And it has definately effects on renal functions and its dose is adjusted in patient with renal insufficiency
Regarding decrease renal insufficiency other factors like old age as with age number of funtioning nephrons decreases and the enlarged prostate can cause back preasure on the urinary system and effect kidney fuction. So these all can contribute to the decrease renal functions.
Hope it helps
Thanks
wishing you best of health
let me know if you have any query
Please consult your doctor before taking any further course of action
Dr M.S Khalil
Note: Consult a Urologist online for consultation about prostate and bladder problems, sexual dysfunction, kidney stones, prostate enlargement, urinary incontinence, impotence and erectile dysfunction - Click here.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
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