question-icon

Does Taking Bupropion And Citalaprom Together Cause Anxiety?

default
Posted on Fri, 2 May 2014
Question: I would like to know if starting bupropion xr150 mg. could cause more anxiety taking it along with citalaprom 20 mg. I just started the bupropion on the 31st of March. my citalopram increased to 20 mg from 10 mg. on the 17th of March. I am more restless and am not sleeping through the night . My anxiety is higher than it was before.
doctor
Answered by Dr. Manisha Gopal (18 minutes later)
Brief Answer: Yes , it can be due to bupropion. Detailed Answer: Hello and welcome to hcm! Both bupropion and escitalopram are good drugs and also used to treat anxiety apart from depression. You said that there is an increase in anxiety from past few days, but it is not clear if--- 1. the anxiety increased after increasing escitalopram from 10 to 20mg (17th March) or 2. after adding bupropion 150mg on 30th March Or It is possible that the new molecule did not suit you we'll enough (some times patient put on bupropion , fluoxetine display increase in anxiety symptoms). In such cases, it is better to discontinue bupropion and start a new drug : venalafaxine or paroxetine. S, if you can correlate the increase in anxiety with starting of bupropion, then it is likely that this is the causative agent and should be stopped a together. Please Donot panic or stress yourself, it does happens sometimes in clinical practice : that a molecule may produce anxiety inspite of reducing it..but the situation is completely manageable and health can be restored. For now, you can take etizolam 0.5mg in morning and in after noon to counter anxiety. this will not give sedation. For sleep at night you may take clonazepam 0.5-1mg. Hope the reply is useful for you Please feel free to ask more questions for clarification. Dr. Manisha Gopal MD Psychiatry
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Manisha Gopal (33 minutes later)
The anxiety increased after the bupropion extended release was added. the citalopram was increased and the 2 weeks before the added bupropion were fine, I do take alprazolam 0.5 mg 3 times a day for anxiety and use zolpidem for sleep. that would keep me asleep until just the last week as well.
doctor
Answered by Dr. Manisha Gopal (18 minutes later)
Brief Answer: best is to stop bupropion Detailed Answer: Hello, It seems clear enough that anxiety increased after bupropion was added, so it is the.causative agent. It is best to stop this drug. If you feel escitalopram 20mg alone can handle the.anxiety well enough then you might not need another molecule. But if it dosent, then you need another good drug along with escitalopram ( as this cannot be increased further, you are already on maximum recommended.dosage of this). You can start paroxetine or venalafaxine to get relief from anxiety completely. It is wise to stop bupropion now. For sleep you can continue zolpidem , but for daytime anxiety it will be good to take 0.5mg etizolam in morning and afternoon in place of alprazolam. Alprazolam is habit forming and may give rebound anxiety, and looses effect over time. I hope the reply is useful for you Do ask if you there are more queries bothering you. Dr. Manisha Gopal MD Psychiatry
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Manisha Gopal (14 minutes later)
I am not on Lexapro. I am on celexa or generic name citalopram. Does this change your answer at all. Sorry for all the bother but want to make sure I have all the information correct.
doctor
Answered by Dr. Manisha Gopal (2 hours later)
Brief Answer: Both are closely related molecules, don't worry Detailed Answer: Hello, Escitalopram is a product of citalopram only, and them properties are almost similar. The only thing is that one can try to increase citalopram to 30mg and see if this helps in anxiety. if 30mg also dosent help, then we should consider adding another molecule to treat anxiety. Bupropion should be discontinued as already mentioned because it is increasing anxiety. I wish you good health, Do ask more queries if there are any doubts Dr. Manisha Gopal MD. Psychiatry
Note: For further guidance on mental health, Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Manisha Gopal

Psychiatrist

Practicing since :2005

Answered : 947 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

159 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
Does Taking Bupropion And Citalaprom Together Cause Anxiety?

Brief Answer: Yes , it can be due to bupropion. Detailed Answer: Hello and welcome to hcm! Both bupropion and escitalopram are good drugs and also used to treat anxiety apart from depression. You said that there is an increase in anxiety from past few days, but it is not clear if--- 1. the anxiety increased after increasing escitalopram from 10 to 20mg (17th March) or 2. after adding bupropion 150mg on 30th March Or It is possible that the new molecule did not suit you we'll enough (some times patient put on bupropion , fluoxetine display increase in anxiety symptoms). In such cases, it is better to discontinue bupropion and start a new drug : venalafaxine or paroxetine. S, if you can correlate the increase in anxiety with starting of bupropion, then it is likely that this is the causative agent and should be stopped a together. Please Donot panic or stress yourself, it does happens sometimes in clinical practice : that a molecule may produce anxiety inspite of reducing it..but the situation is completely manageable and health can be restored. For now, you can take etizolam 0.5mg in morning and in after noon to counter anxiety. this will not give sedation. For sleep at night you may take clonazepam 0.5-1mg. Hope the reply is useful for you Please feel free to ask more questions for clarification. Dr. Manisha Gopal MD Psychiatry