Gall Bladder Stones Removed, Elevated LFTs, Persisting Pain After Surgery
Thanks for the query.
Pain in the Right Upper Quadrant following cholecystectomy (postcholecystectomy syndrome) is usually secondary to
1) Unrelated causes like Gastritis, Peptic Ulcer Disease
2) Retained Common Bile Duct stone - unlikely as MRCP is normal
3) Sphincter of Oddi dysfunction - The sphincter present at the junction of Common Bile Duct and duodenum is spastic and does not relax during meal causing symptoms. Diagnosis is difficult as a dilated CBD may be found only during the pain and is associated with liver enzyme elevation.
The elevated enzymes in your case may suggest the above or a condition called Nonalcoholic Steatohepatitis as all other common causes of enzyme elevation have been ruled out.
This may be evident on an Ultrasound of the abdomen and the pattern of enzyme elevation.
Hope your concern is addressed. In case of any doubts, I am available for the follow ups.
Regards.
Thanks for writing again.
The ultrasound correlate of XXXXXXX (Non-alcoholic Steatohepatitis) is a bright liver.
Liver biopsy is a tool to look at the cause and extent of liver inflammation that is employed once the noninvasive tests have failed to point towards a source.
One has to test for autoimmune hepatitis markers like XXXXXXX (Anti Nuclear Antibody), SMA (Smooth muscle Antibody), LKM (Liver Kidney Microsome) and probable iron overload also.
It is also advisable to get a HBV DNA (Hepatitis B Virus- Deoxy Ribo Nucleic Acid) and HCV RNA (Hepatitis C Virus- Ribo Nucleic Acid) tested before going to liver biopsy.
I hope this answers your query.
Wish you good health.
Regards