HBV Quantitative Real Time-PCR Testing Done. Hepatitis B E Antigen Present. Future Treatment?

Posted on Thu, 21 Jun 2012

Question: what does HBV Quantitative Real time - PCR with result 250 copies / ml plasma mean? If the same is for Antibodies to Hepatitis B 'e' Antigen (anti-HBe). What is the future treatment for the same

Answered by Dr. Ketan Vagholkar (3 hours later)

Hi

PCR testing is done to assess the viral load in the patient. If these values are high, it suggests that the viruses are still actively multiplying in the body.

The persistent presence of HBeAg suggests high infectivity in the patient.
The status of the liver has to be ascertained by biopsy and transaminase estimation. This can be followed by two types of medications,1 antiviral drugs and 2. interferon therapy. The response to either treatment depends upon the genome of the viral particle. Few genomes respond well while few may not. This is the time to commence antiviral treatment provided the liver status permits depending upon the biopsy and enzyme levels.

A follow up with the Gastroenterologist regularly is suggested and institute the treament as required.

Hope I answered your question.

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar