
Had Complete Hysterectomy Due To Endometriosis. On Synthroid. Noticed T3 Dropping From To 260 To 230. Having Hot Flashes. Remedy?

Question: Hello, I had a full hysterectomy several years ago due to endometriosis and I have no thyroid as of 2006. I am a fitness instructor, 43 yrs old. Things have been fine on 100 mcg of synthroid along with .05 of Estradiol. However, I am noticing some changes in my thyroid levels although I am still in the normal range. My free t3 has dropped from 260 to 230 in an 8 month period (range is 200-440 pg/dl), my free T4 remains the same as last year 1.44, range is 0.930-1.70ng/dl, and my TSH was .71, 8 months ago, and now it is 1.03, range is 0.27-4.20 mcIU/ml. About a month ago, I started to have hot flashes especially at night interrupting my sleep. The dr. that performed my surgery wants to up my estrogen to.075 twice a week minveille patch, but I don't want to become hypothyroid. Does the estrogen increase free t3 or decrease it? I would like to see my free t3 not declining while the TSH is increasing.
Brief Answer:
Stepping up the estrogen will help
Detailed Answer:
Hi,
Thanks for your query.
There is connection between the estrogen and the thyroid feed back mechanism. low estrogen levels can reduce the t3 levels by a narrow range.
Stepping up estrogen can alter the t3 levels and bring it to normal. If this fails then you may have to get the Synthroid medication revised.
Hope, I answered your query.
Please let me know if there are any other concerns.
regards,
Stepping up the estrogen will help
Detailed Answer:
Hi,
Thanks for your query.
There is connection between the estrogen and the thyroid feed back mechanism. low estrogen levels can reduce the t3 levels by a narrow range.
Stepping up estrogen can alter the t3 levels and bring it to normal. If this fails then you may have to get the Synthroid medication revised.
Hope, I answered your query.
Please let me know if there are any other concerns.
regards,
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar


Brief Answer:
Yes, the levels are interconnected
Detailed Answer:
Hi,
Estrogen has influence on the pituitary gland which secretes TSH, low estrogen stimulates increased production of TSH. Also the release of TSH is controlled by free T3 levels in the blood. Lower levels of T3 in blood cause rise in release of TSH.
This is a receptor mediated mechanism and changes in the any hormone reflect very quick in other.
Hope, I cleared your doubt.
regards,
Yes, the levels are interconnected
Detailed Answer:
Hi,
Estrogen has influence on the pituitary gland which secretes TSH, low estrogen stimulates increased production of TSH. Also the release of TSH is controlled by free T3 levels in the blood. Lower levels of T3 in blood cause rise in release of TSH.
This is a receptor mediated mechanism and changes in the any hormone reflect very quick in other.
Hope, I cleared your doubt.
regards,
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar


Yes, you did. Thank you for the clarification.
I have one final question--Can an increase in fitness level cause one to metabolize estrogen at a faster rate therefore causing a need for an increase in estrogen? --Just trying to figure out why the change all of the sudden for me.
I have one final question--Can an increase in fitness level cause one to metabolize estrogen at a faster rate therefore causing a need for an increase in estrogen? --Just trying to figure out why the change all of the sudden for me.
Brief Answer:
No, fitness level is does alter the levels
Detailed Answer:
Hi,
No, there is no relation between the physical fitness and metabolism of the estrogen or any other hormones.
Regards,
No, fitness level is does alter the levels
Detailed Answer:
Hi,
No, there is no relation between the physical fitness and metabolism of the estrogen or any other hormones.
Regards,
Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar

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