
How Long After Discontinuing Antidepressant Can St John's Wort Be Taken?

Question: How long I have to wait after stopping antidepressant to take St John's wort, thank for your help
Brief Answer:
At least one week needed to clear the drugs
Detailed Answer:
Hello, Welcome to Health Care Magic
I can understand your concern. Most of antidepressants act by increasing serotonergic neurotransmission in brain. St John's Wort also increase serotonin in brain. Taking antidepressants with St Johns Wort may cause serotonin syndrome. It is advisable to start the drug at least a week after stopping the antidepressants. Special precautions should be used while on SSRIs.
Thanks, Hope this helps you, if you have more doubts you can ask again.
Take care
At least one week needed to clear the drugs
Detailed Answer:
Hello, Welcome to Health Care Magic
I can understand your concern. Most of antidepressants act by increasing serotonergic neurotransmission in brain. St John's Wort also increase serotonin in brain. Taking antidepressants with St Johns Wort may cause serotonin syndrome. It is advisable to start the drug at least a week after stopping the antidepressants. Special precautions should be used while on SSRIs.
Thanks, Hope this helps you, if you have more doubts you can ask again.
Take care
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Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar

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