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How Long Should I Take Combutol And Pyzina For TB?
Question: Test report for TB negatie.before that started ccombutol 1000 aad pyzina .how long shd I take though all reorts r negatie
Brief Answer:
6 months of treatment required.
Detailed Answer:
Thanks for your query at HCM.
I understand your concern and situation.
What are were your symptoms? If pulmonary tuberculosis then treatment is required for 6 months and extra pulmonary tuberculosis treatment for 8 months. Rifampicin, Isoniazid, pyrazinamide and ethambutol for 2 months and after that only ethambutol and pyrazinamide for 4 months. Test for tuberculosis by sputum microscopy for acid fast staining is done 0, 2, 4, 6 months to declare patient cure in pulmonary tuberculosis. Take your medicines on time without missing even a single dose to prevent resistance. If sputum is positive after 3 months the drugs needed to be changed. So remain in follow-up. Eat protein rich balanced diet with multivitamins and calcium supplements.
You can take a follow-up query.
If no clarifications then you can close the discussion and rate the answer.
Dr. Sheetal Verma
Infectious diseases Specialist
6 months of treatment required.
Detailed Answer:
Thanks for your query at HCM.
I understand your concern and situation.
What are were your symptoms? If pulmonary tuberculosis then treatment is required for 6 months and extra pulmonary tuberculosis treatment for 8 months. Rifampicin, Isoniazid, pyrazinamide and ethambutol for 2 months and after that only ethambutol and pyrazinamide for 4 months. Test for tuberculosis by sputum microscopy for acid fast staining is done 0, 2, 4, 6 months to declare patient cure in pulmonary tuberculosis. Take your medicines on time without missing even a single dose to prevent resistance. If sputum is positive after 3 months the drugs needed to be changed. So remain in follow-up. Eat protein rich balanced diet with multivitamins and calcium supplements.
You can take a follow-up query.
If no clarifications then you can close the discussion and rate the answer.
Dr. Sheetal Verma
Infectious diseases Specialist
Above answer was peer-reviewed by :
Dr. Vinay Bhardwaj
Started 0N 29/9/14 with chest pain at left side in sleeping and bending position.Pleural aspiration in mild scapular line in 5th intercostal space.Nearly 300ml straw colored fluid obtained. used FIRECCOX PO ONCE DAILY 2 TABS FOR 20 DAYS. ct chest; known case of left pleural effusion of ? TB origin to rule out malignancy. No demonstrable mas lesions. Moderate left pleural effusion with collaps of Basal lung segments. Collapse consolidation in lingular lobe.Pleuroparenchymal fibrotic bands in medial segment right middle lobe Small septated subpleural pneumatocele in right upper lose. PET CT WHOLEBODY HYPERMETABOLIC BILATERAL BULKY NODULAR ADRENAL GLAND NOTED AS DESCRIBED. MILD LEFT PLEURAL EFFUSION NOTED. NO OTHER EVIDENCE OF METAOLICALLY ACTIVE DISEASE IN PRESENT WHOLE BODY SCAN. TB PCR..PLEURAL FLUID ...MYCOBACTERIUM TB..NOT DETECTED MYCCOBACTERIUM OTHER THAN TB ...NOT DETECTED SMEAR....ACID FAST BACILLI NOT SEEN..AFB CCULTURE; NO GROWTH DETECTED AT THE END OF SIXTH WEEK. USED TAB;;'PYZINA(twice) 750, R. CINEX, ETHAMBUTOL 1000, BENADONA.On receipts of reports stopped. untii then R. CINEX USED FOR10 DAYS.REMAINING CONInTUED .SOFAR 5 MONTHS12 DAYS. Now issue is whether I ccan stopp Pyzina, Combutol and Benadona. from 31st March 2012.
Thanks/regards
Thanks/regards
Brief Answer:
Atleast 6 months
Detailed Answer:
Welcome back.
I want to know if you your symptoms have resolved. If yes then definitely you had TB. Sometimes TB PCR TEST is negative as sensitivity is low and same for culture. But fluid cytology for giant cell should also have been done. As far as your treatment I don't agree it was not according to any guidelines. Rifampicin which is most important drug must have been taken for complete 6 months with isoniazid. I disagree with your doctor completely he must have not stopped this. Ethambutol and pyrazinamide for 2 months. If this regime is not followed there is a high chance of resistance in future when drugs become ineffective. Seeing your present scenario kindly take the drugs for 6 months. After that get X RAY once and sputum examination at least 3 times to see tb bacteria. Also get LFT and kidney function TEST done.
Stay in touch for follow-up.
Best of health
Atleast 6 months
Detailed Answer:
Welcome back.
I want to know if you your symptoms have resolved. If yes then definitely you had TB. Sometimes TB PCR TEST is negative as sensitivity is low and same for culture. But fluid cytology for giant cell should also have been done. As far as your treatment I don't agree it was not according to any guidelines. Rifampicin which is most important drug must have been taken for complete 6 months with isoniazid. I disagree with your doctor completely he must have not stopped this. Ethambutol and pyrazinamide for 2 months. If this regime is not followed there is a high chance of resistance in future when drugs become ineffective. Seeing your present scenario kindly take the drugs for 6 months. After that get X RAY once and sputum examination at least 3 times to see tb bacteria. Also get LFT and kidney function TEST done.
Stay in touch for follow-up.
Best of health
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
CLINICAL HISTORY;; HTN,DM
THE FOLLOWINGG TESTS ALSO DONE:
TEST RESULTS
24 HRS. URINARY METANEPHRINE VOL 4300ML 1.37mg/24 hrs method:enzyme linked immunosorbent assay
catecholamines, urine
ADRENALIN,URINE 2.1 ug/24 HR
NOR-ADRENALIN, URINE 15.5ug/24hr A
CYTOLOGY REPORT
30 ML YELLOWISH COLOURED PLEURAL FLUID ;; SMEARS PREPARED FROM CENTRIFUGED DEPOSITS OF PLEURAL FLUID STUDIED. MODERATELY CELLULAR SMEARS. CHRONIC INFLAMMATORY CELLS CONSISTING OF SMALL MATURE LYMPHOCYTIC CELLS ARE SEEN AGAINST RBCn BACKGROUND INTENSE REACTIVE MESOTHELIAL CELL POPULATION IS SEEN. NO EVIDENCE OF NUCLEAR ATYPIA. NO EVIDENCE OF MALIGNANCY.COMMENTS;;; PLURAL FLUID;; NEGATIVE FOR MALIGNANT CELLS. SHOWS LYMPHOCYTIC PLEOCYTOSIS.
THE FOLLOWINGG TESTS ALSO DONE:
TEST RESULTS
24 HRS. URINARY METANEPHRINE VOL 4300ML 1.37mg/24 hrs method:enzyme linked immunosorbent assay
catecholamines, urine
ADRENALIN,URINE 2.1 ug/24 HR
NOR-ADRENALIN, URINE 15.5ug/24hr A
CYTOLOGY REPORT
30 ML YELLOWISH COLOURED PLEURAL FLUID ;; SMEARS PREPARED FROM CENTRIFUGED DEPOSITS OF PLEURAL FLUID STUDIED. MODERATELY CELLULAR SMEARS. CHRONIC INFLAMMATORY CELLS CONSISTING OF SMALL MATURE LYMPHOCYTIC CELLS ARE SEEN AGAINST RBCn BACKGROUND INTENSE REACTIVE MESOTHELIAL CELL POPULATION IS SEEN. NO EVIDENCE OF NUCLEAR ATYPIA. NO EVIDENCE OF MALIGNANCY.COMMENTS;;; PLURAL FLUID;; NEGATIVE FOR MALIGNANT CELLS. SHOWS LYMPHOCYTIC PLEOCYTOSIS.
Brief Answer:
Suggestive of TB
Detailed Answer:
Hi
According to your reports chronic inflammatory cells and lymphocytes are seen in tuberculosis infection. So to start anti-tuberculosis treatment was appropriate. But in treatment Rifampicin must have been prescribed too.
Take care.
Suggestive of TB
Detailed Answer:
Hi
According to your reports chronic inflammatory cells and lymphocytes are seen in tuberculosis infection. So to start anti-tuberculosis treatment was appropriate. But in treatment Rifampicin must have been prescribed too.
Take care.
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..
Above answer was peer-reviewed by :
Dr. Vinay Bhardwaj
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