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Is PSA Level Of 0.3 Ng/ml/gm A Cause For Concern?

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Posted on Mon, 4 Jul 2016
Question: Is PSA level of 19ng/ml is acceptable with a prostate size of 80 gms. As i heard that each gram of BPH tissue increases PSA level by 0.3 ng/ml/gm. Total prostate volume is 79.2 cc
doctor
Answered by Dr. Dr. P. T. Patil (50 minutes later)
Brief Answer:
Needs to rule out cancer of Prostate by doing Prostate Biopsy

Detailed Answer:
Hello
Thanks for your query ,based on the facts that you have posted it appears that your Serum P.S.A.levels are persistently higher than normal value of 4 ng/ml.

PSA level is raised in following conditions
1) Benign enlargement of prostate .
2 Cancer of the prostate.
3)Chronic infection of Prostate (Chronic Prostatitis)

However it is international protocol that persistent level of raised PSA is always suspected to be due Cancer of the Prostate unless proved otherwise by doing Ultrasound Guided Multicore Prostate Biopsy .

Please discuss this with your Urologist and get Prostate Biopsy done to rest assured about the diagnosis .This will help you to relieve mental tension.

Hope I have answered your query ,please feel free to ask if you have more questions , I shall be happy to help you .
Thanks and Regards.
Dr.Patil.



Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. P. T. Patil (10 minutes later)
Does bph increases psa level by 0.3ng/ml/gm.
doctor
Answered by Dr. Dr. P. T. Patil (13 minutes later)
Brief Answer:
Increase of 0.3 ng of PSA with 1 gm of BPH is not universally accepted

Detailed Answer:
Hello
Thanks for follow up .

PSA is expressed by the cancer tissues at 3ng/ml in the blood per gram of cancer, as against 0.3ng/ml/gm of tissue in BPH.

To be more specific in BPH we consider only the Adenoma (Binign tumor) in prostate and not the entire volume and weight of the prostate .

It is a standard protocol accepted and followed by Urologist all over the world to get tissue from the prostate by biopsy to confirm the tissue diagnosis rather than to rely on PSA values which are most variable and unreliable .

PSA is a screening test to decide about need for Prostate Biopsy and does not confirm the diagnosis of cancer of prostate and for deciding the mode of treatment .

Thanks and Regards.
Dr.Patil.
Note: Consult a Urologist online for consultation about prostate and bladder problems, sexual dysfunction, kidney stones, prostate enlargement, urinary incontinence, impotence and erectile dysfunction - Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
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Dr. Dr. P. T. Patil

Urologist

Practicing since :1971

Answered : 10590 Questions

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Is PSA Level Of 0.3 Ng/ml/gm A Cause For Concern?

Brief Answer: Needs to rule out cancer of Prostate by doing Prostate Biopsy Detailed Answer: Hello Thanks for your query ,based on the facts that you have posted it appears that your Serum P.S.A.levels are persistently higher than normal value of 4 ng/ml. PSA level is raised in following conditions 1) Benign enlargement of prostate . 2 Cancer of the prostate. 3)Chronic infection of Prostate (Chronic Prostatitis) However it is international protocol that persistent level of raised PSA is always suspected to be due Cancer of the Prostate unless proved otherwise by doing Ultrasound Guided Multicore Prostate Biopsy . Please discuss this with your Urologist and get Prostate Biopsy done to rest assured about the diagnosis .This will help you to relieve mental tension. Hope I have answered your query ,please feel free to ask if you have more questions , I shall be happy to help you . Thanks and Regards. Dr.Patil.