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Is Zyprexa A Dopamine Antagonist?

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Posted on Wed, 7 Dec 2016
Question: is zyprexa a dopamine antogonist?
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Answered by Dr. Dariush Saghafi (3 hours later)
Brief Answer:
Yes- Antagonizes ALL subtypes of Dopamine receptors

Detailed Answer:
Good evening and thank you for your question. The very concise and to the point response to your question is:

YES. Olanzapine or ZYPREXA fully antagonizes all Dopamine Subtype receptors. There are 5 basic receptor subtypes, D1-D5 with D1 being the most plentiful while D4 is primarily associated with the ANTIPARKINSONIAN properties we we see when medications to treat Parkinson's disease are used. Other dopamine receptors have different primary functions.

The pharmacological action of OLANZAPINE is to effectively antagonize ALL subtypes of dopamine receptors.

If I've adequately answered your questions could you do me a huge favor by CLOSING THE QUERY and being sure to include some fine words of feedback along with a 5 STAR rating if you feel my suggestions have helped? Again, many thanks for posing your questions and please let me know how things turn out.

Do not forget to contact me in the future at: www.bit.ly/drdariushsaghafi for additional questions, comments, or concerns having to do with this topic or others.

This query has utilized a total of 26 minutes of professional time in research, review, and synthesis for the purpose of formulating a return statement.
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Dariush Saghafi

Neurologist

Practicing since :1988

Answered : 2472 Questions

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Is Zyprexa A Dopamine Antagonist?

Brief Answer: Yes- Antagonizes ALL subtypes of Dopamine receptors Detailed Answer: Good evening and thank you for your question. The very concise and to the point response to your question is: YES. Olanzapine or ZYPREXA fully antagonizes all Dopamine Subtype receptors. There are 5 basic receptor subtypes, D1-D5 with D1 being the most plentiful while D4 is primarily associated with the ANTIPARKINSONIAN properties we we see when medications to treat Parkinson's disease are used. Other dopamine receptors have different primary functions. The pharmacological action of OLANZAPINE is to effectively antagonize ALL subtypes of dopamine receptors. If I've adequately answered your questions could you do me a huge favor by CLOSING THE QUERY and being sure to include some fine words of feedback along with a 5 STAR rating if you feel my suggestions have helped? Again, many thanks for posing your questions and please let me know how things turn out. Do not forget to contact me in the future at: www.bit.ly/drdariushsaghafi for additional questions, comments, or concerns having to do with this topic or others. This query has utilized a total of 26 minutes of professional time in research, review, and synthesis for the purpose of formulating a return statement.