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Is A Repetition Of Hepatitis A After 6 Months For A EBV Patient?
Question: Hello
Daughter had EBV and CMV on which I asked prior questions re possibly being immuno-compromised and need for revaccination. Dateline is diagnosed 10 march, revaccinated with Hep A and Hep B booster 24 March and follow up blood tests 28 April.
1 Checking that these results are fine.She now has HAV antibody level of 23.3mlU/mL (report said above 20mlU/mL considered proactive antibody levels) and her Hep B was very high at over 1000 mlU/mL (reposrt said over 10mlU/mL is considered proactive antibody level)? Should I be worried it's so high? DO I need to get her to do 2nd Hep A vaccination after 6 mths?
2 She also tested to still have rubella & varicella immunity so told need to vaccinate for anything else.e.g. TB. Is that correct?
3 Her liver function and immunoglobulins were normal but no mention of the heptocellular dysfunction previously reported in earlier tests (when EBV diagnosed). Should I be worried about that? I've been told with revaccination there's a chance for antibodies to mutate (for want of a better word?).
4 Did her reaction to the penicillin (swollen throat & slight rash) in antibiotics when she had the acute EBV & CMV create any antibody mutation or resistance I should be concerned about? She's about to travel and live overseas aged 18 yrs thinking she's bullet proof. I wish to ensure she's fully aware and whether she should be doing anything else? E.g. needing higher hygiene practices or other vaccination if she visits third world countries?
Daughter had EBV and CMV on which I asked prior questions re possibly being immuno-compromised and need for revaccination. Dateline is diagnosed 10 march, revaccinated with Hep A and Hep B booster 24 March and follow up blood tests 28 April.
1 Checking that these results are fine.She now has HAV antibody level of 23.3mlU/mL (report said above 20mlU/mL considered proactive antibody levels) and her Hep B was very high at over 1000 mlU/mL (reposrt said over 10mlU/mL is considered proactive antibody level)? Should I be worried it's so high? DO I need to get her to do 2nd Hep A vaccination after 6 mths?
2 She also tested to still have rubella & varicella immunity so told need to vaccinate for anything else.e.g. TB. Is that correct?
3 Her liver function and immunoglobulins were normal but no mention of the heptocellular dysfunction previously reported in earlier tests (when EBV diagnosed). Should I be worried about that? I've been told with revaccination there's a chance for antibodies to mutate (for want of a better word?).
4 Did her reaction to the penicillin (swollen throat & slight rash) in antibiotics when she had the acute EBV & CMV create any antibody mutation or resistance I should be concerned about? She's about to travel and live overseas aged 18 yrs thinking she's bullet proof. I wish to ensure she's fully aware and whether she should be doing anything else? E.g. needing higher hygiene practices or other vaccination if she visits third world countries?
Brief Answer:
No need to worry for this high Hepatitis B antibody titer.
Detailed Answer:
Thanks for your question on Healthcare Magic.
I can understand your concern.
Answer to your 1st question.
No need to worry for this high levels of hepatitis B antibody. No harm in it. No need for repeat hepatitis A vaccine after 6 months.
Answer to your 2nd question.
I think the doctor is talking about adult pulmonary vaccines like pneumococcal and influenza vaccines.
Answer to your 3rd question.
No need to worry for hepatocellular damage because her liver functions are normal. And the word is shift and drift. Yes, there are chances of these mutational changes but chances are very less.
Answer to your 4th question.
I don't think, penicillin sensitivity will cause any antibody shift or drift.
In my opinion, you should discuss about giving her adult pulmonary vaccines like pneumococcal and influenza vaccines to prevent recurrent respiratory tract infection.
Hope I have solved your query. I will be happy to help you further
Wishing good health to your daughter. Thanks.
No need to worry for this high Hepatitis B antibody titer.
Detailed Answer:
Thanks for your question on Healthcare Magic.
I can understand your concern.
Answer to your 1st question.
No need to worry for this high levels of hepatitis B antibody. No harm in it. No need for repeat hepatitis A vaccine after 6 months.
Answer to your 2nd question.
I think the doctor is talking about adult pulmonary vaccines like pneumococcal and influenza vaccines.
Answer to your 3rd question.
No need to worry for hepatocellular damage because her liver functions are normal. And the word is shift and drift. Yes, there are chances of these mutational changes but chances are very less.
Answer to your 4th question.
I don't think, penicillin sensitivity will cause any antibody shift or drift.
In my opinion, you should discuss about giving her adult pulmonary vaccines like pneumococcal and influenza vaccines to prevent recurrent respiratory tract infection.
Hope I have solved your query. I will be happy to help you further
Wishing good health to your daughter. Thanks.
Note: For further information on diet changes to reduce allergy symptoms or to boost your immunity, Ask here.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
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