HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

question-icon

Is High Dose Intravenous Vitamin C Advisable For Chronic Hepatitis B?

default
Posted on Mon, 12 Jun 2017
Question: Would you recommend high dose intravenous vitamin c for patient with chronic hepatitis b.
doctor
Answered by Dr. Sunil (23 minutes later)
Brief Answer:
yes you could give it a try,under research topic.No solid documented proofs are there.

Detailed Answer:
Hi,
Thanks for choosing HealthcareMagic for your query dear,
Have gone through your details and i appreciate your concerns.

Though this treatment is still under research yet latest trials have shown that high dose intravenous vitamin C therapy has a positive effect on duration of disease and significantly reduces viral antibody levels and reduces the risk of complications in future.
High extracellular levels of ascorbic acid are reported to have anti-viral effects in humans and animals. Ascorbic acid generates extracellular hydrogen peroxide, which releases free oxygen radicals which destroys cells infected with viruses, including HBV, but not to normal cells.
Though this method is still in research yet safety index are very high and can be given a trial.However documented text book proofs are still not available.

Thanks
Above answer was peer-reviewed by : Dr. Prasad
doctor
default
Follow up: Dr. Sunil (27 minutes later)
Do you think the future cure of hepatitis b would include intravenous vitamine c therapie
doctor
Answered by Dr. Sunil (5 minutes later)
Brief Answer:
Follow up answer.

Detailed Answer:
Hi again,
Yes off course apart from vitamin C a number of other drugs are under trial some of them in thier last phases.

There are two new tenofovir prodrugs, called TAF and CMX 157, that are more effective at reaching liver cells and impeding HBV replication. TAF is now in Phase III clinical trials and is expected to reach the U.S. Food and Drug Administration (FDA) soon.
Myrcludex B is an experimental drug for the treatment of hepatitis B and D. The first Phase IIa clinical trials with 40 patients concluded in 2014. A dose-dependent effect on HBV DNA was observed HBV DNA decline at week 12 occurred in (75%) patients receiving 10mg Myrcludex B.

One of the more advanced molecular strategies, already in Phase II trials, is a “silencing” RNA process. This approach uses RNAi gene silencers to target and destroy HBV RNA to prevent viral reproduction. “CccDNA remains,” Block explained, “but all of its gene products it needs are choked.”it will take about 5-10 years time to be out in market.
Apart from them a number of othe drugs are under trial phase at present.
Rest assure there will be many new options in next 5-8 years.

Thanks.
Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
default
Follow up: Dr. Sunil (11 minutes later)
Do you think those in the last phase would cure completely hepatitis b
doctor
Answered by Dr. Sunil (4 minutes later)
Brief Answer:
Follow up.

Detailed Answer:
Hi again,

Till date, the results are excellent so we can say that we are near cure(informally).

However, still, these words are not documented in any of the standards books.
But as a gastroenterologist going through the publications and results of the trial I feel that researchers are near the cure.


Regards.
Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
default
Follow up: Dr. Sunil (30 minutes later)
Thanks for the answer. I was thinking i should try homeopathic therapie for the cure. Do you think i should do that. Have you ever had a chronic patient with hepatitis b who became later negative of the virus because of homeopathic therapie
doctor
Answered by Dr. Sunil (13 hours later)
Brief Answer:
Definitely yes.

Detailed Answer:
Hi again,
I suffered from Meniere's disease for 13 years.You can read about this on google. I tried every possible treatment in modern medicine but was not at all relieved.However after 13 years of unsuccesful treatment i decided to go for homeopathy. Though i have no faith on homeopathy but i decided to give it a try.

It has been more then 1 year and i din't had another attack of vertigo since then(earlier i use to have them every second day).I am still on medication. So definitely you should try homeopathy but first thing is that get a good physician. Not all homeopath's are good in making diagnosis.

Regards.


Above answer was peer-reviewed by : Dr. Kampana
doctor
default
Follow up: Dr. Sunil (13 minutes later)
Would you recommend me a good physician . Do you know any goid physician for homoepathic theurapie around the world. I am willing to travel
doctor
Answered by Dr. Sunil (13 minutes later)
Brief Answer:
Follow up.

Detailed Answer:
Hello again,
My Homeopath(who cured my meniere's) is located in New Delhi(Capital of india).

Dr. Bimal Gosain
+0000

210,Sector -14, Gurgaon(India)
About 45 minutes from Indiragandhi international airport ,NewDelhi
While taking your history he would ask you a number of questions which may look irrelevent to you,But take all questions seriously.
Wish you great luck.
No previous appointments required.
In case you need any other help feel free to ask.


Thanks.

Above answer was peer-reviewed by : Dr. Kampana
doctor
default
Follow up: Dr. Sunil (29 minutes later)
Thanks so much. I will call him incha allah
doctor
Answered by Dr. Sunil (12 minutes later)
Brief Answer:
Get well soon.

Detailed Answer:
Your Most welcome.

Get well soon.
Above answer was peer-reviewed by : Dr. Nagamani Ng
doctor
default
Follow up: Dr. Sunil (20 minutes later)
Do you think i should fast for the ramadan. I really want to but at the same time i am concern about my condition
doctor
Answered by Dr. Sunil (1 hour later)
Brief Answer:
Overall fasting enhances HBV RNA and DNA synthesis.

Detailed Answer:
Hello again Dear,

As per the trials done on mouse for reviewing the effect of Fasting on Hepatitis B it has been demonstrated that secreted HBV e antigen (HBeAg) encoded by the precore is increased approximately 40% as a consequence of fasting for 48 h. Consistent with this observation, fasting is associated with approximately the same increase in viral RNA synthesis.And in Ramdan you need to fast for 30 days so i won't suggest you to fast.Overall, results suggest that fasting enhances HBV RNA and DNA synthesis to a modest extent.

Regards.
Note: For further follow up on digestive issues share your reports here and Click here.

Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
Answered by
Dr.
Dr. Sunil

Gastroenterologist

Practicing since :1982

Answered : 351 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

159 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
Is High Dose Intravenous Vitamin C Advisable For Chronic Hepatitis B?

Brief Answer: yes you could give it a try,under research topic.No solid documented proofs are there. Detailed Answer: Hi, Thanks for choosing HealthcareMagic for your query dear, Have gone through your details and i appreciate your concerns. Though this treatment is still under research yet latest trials have shown that high dose intravenous vitamin C therapy has a positive effect on duration of disease and significantly reduces viral antibody levels and reduces the risk of complications in future. High extracellular levels of ascorbic acid are reported to have anti-viral effects in humans and animals. Ascorbic acid generates extracellular hydrogen peroxide, which releases free oxygen radicals which destroys cells infected with viruses, including HBV, but not to normal cells. Though this method is still in research yet safety index are very high and can be given a trial.However documented text book proofs are still not available. Thanks