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Pregnant, Can't Keep Down Anything In Stomach In Hyperemesis Gravidarum. What To Do?

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Posted on Mon, 21 Oct 2013
Question: if a lady can,t keep downanything in stomach in hyperemesis gravidarum. How to manage the situation?
doctor
Answered by Dr. Sree Gouri SR (35 minutes later)
Brief Answer:
oral and intravenous fluid replacement

Detailed Answer:
Hi,
Thanks for the query.
Some amount of nausea and vomiting are common in pregnancy.
If woman presents with hyperemesis gravidarum, the measures to be followed are :
-Oral antiemetics with combination of doxalamine and pyridoxine are approved to use in pregnancy.
-The lost fluids and electrolytes should be replaced in small quantities at frequent intervals.
-If patient not able to take anything orally, intravenous infusion should be given.
Among the intravenous fluids, half of the amount should be 5% dextrose.
-Intravenous antacids and antiemetics can be given.
-Once the vomitings get controlled oral fluids can be started.
-The cause of the hyperemesis to be investigated. It can be seen in conditions like twin gestation, molar pregnancy etc . So these conditions should be ruled out.
-Presence of urinary ketonebodies to be investigated to estimate the severity of the condition.
Hope I have answered your query. I will be available to answer followup queries. If you are satisfied with the answer, please give your review at the end of the discussion.
Take care.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sree Gouri SR (13 minutes later)
Is tranexamic acid tablet contraindicated in pregnancy?
Is rabeprazoie 20 mg tab cotraindicatedin pregnancy?
doctor
Answered by Dr. Sree Gouri SR (31 minutes later)
Brief Answer:
can be used according to studies

Detailed Answer:
Hi,
No, rabeprazole can be used in pregnancy according to the studies.
It belongs to category B drug in pregnancy according to FDA.
Means animal studies excluded the risk of teratogenicity but sufficient human studies are lacking.
Take care.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sree Gouri SR (5 hours later)
Piease inform me about the use of tranexamic acid tablet [Brand name Happy ] is safe in pregnancy or not.
PLease tell me about domstal tab is safe in pregnancy
doctor
Answered by Dr. Sree Gouri SR (2 hours later)
Brief Answer:
Category C drug

Detailed Answer:
Hi,
Domstal tablet contains domperidone.
Which belongs to category C drugs in pregnancy according to FDA. Means animal studies have shown some adverse effects but human studies are lacking.
In general use no adverse effects reported because of domperidone.
But better to use first line drugs like doxinate as per as possible.
Take care.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sree Gouri SR (48 hours later)
is diclofenac diethyamine as local application for relief of pain contraindicated in pregnancy?
doctor
Answered by Dr. Sree Gouri SR (2 hours later)
Brief Answer:
better to avoid in late pregnancy

Detailed Answer:
Hi,
Topical diclofenac belongs to category C drugs in pregnancy up to 30 weeks and category D drugs after 30 weeks.
Better to avoid especially in late pregnancy, because it can affect the baby by its prostaglandin inhibiting effect.
So better to use other preparations like paracetamol preparations etc.
Take care.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Sree Gouri SR

OBGYN

Practicing since :2006

Answered : 5839 Questions

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Pregnant, Can't Keep Down Anything In Stomach In Hyperemesis Gravidarum. What To Do?

Brief Answer:
oral and intravenous fluid replacement

Detailed Answer:
Hi,
Thanks for the query.
Some amount of nausea and vomiting are common in pregnancy.
If woman presents with hyperemesis gravidarum, the measures to be followed are :
-Oral antiemetics with combination of doxalamine and pyridoxine are approved to use in pregnancy.
-The lost fluids and electrolytes should be replaced in small quantities at frequent intervals.
-If patient not able to take anything orally, intravenous infusion should be given.
Among the intravenous fluids, half of the amount should be 5% dextrose.
-Intravenous antacids and antiemetics can be given.
-Once the vomitings get controlled oral fluids can be started.
-The cause of the hyperemesis to be investigated. It can be seen in conditions like twin gestation, molar pregnancy etc . So these conditions should be ruled out.
-Presence of urinary ketonebodies to be investigated to estimate the severity of the condition.
Hope I have answered your query. I will be available to answer followup queries. If you are satisfied with the answer, please give your review at the end of the discussion.
Take care.