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Should Steroid Dosage Be Increased For Increased CPK Levels?

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Posted on Mon, 23 Jun 2014
Question: My ESR Levels from 80 , came down to 18 . But after reducing Wysolone from 10 Mg alternate days . It was further reduced to 5 MG alternate days . My CPK Levels gone up from 100 to 456. Normal range is 308. My doctor advised to take CPK & SGOT after 2 weeks. Should the steroid to be increased to 10MG alternative days. Last 6 months i am in 5 Mg alternate days . Any side effects on using this lesser Mg steriod.

Wysolone - 30 MG for 60 days , dropped week on week currently at 5mg alternate days . Calicum 500 mg , Vitamin tablet . Current ESR -18 , CPK - 456 ( Normal 308).
doctor
Answered by Dr. Dr. Rahul Kumar (38 minutes later)
Brief Answer:
details of disease required

Detailed Answer:
Hello
It is important for me to know why you were taking steroids daily.
I will be able to comment on details regarding doses only after knowing the details of your disease.
Thank you
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. Rahul Kumar (7 minutes later)
I am taking Steroid alternate Day - 5 Mg - Wysolone .

I have been diganoised - LE TUMIDUS 2 year back - DLE - Mucin creation . My ANA was + ve. But i have taken ANA DNA -SLE is negative .

Medication was only HCQS - once a day .

Last year , i was diagnonised dermatomyositis / Polymyositis . CPK -1080 and ESR-80. I had Wysolone 30 mg for 2 months , later tapperred slowly to 5mg alternative days,. My CPK was normal , till i used 10 mg alternative days.

Now during my recent Blood Test , CPK had claimed to 456 , But ESR Levels at 18.

Should Steroid to be increased from 10 Mg alternative days (or) continue with same 5Mg steroid alternate days.






doctor
Answered by Dr. Dr. Rahul Kumar (43 hours later)
Brief Answer:
Dont worry about enzyme levels

Detailed Answer:
Hello
Thanks for the details.
You are suffering from autoimmune disorders.
Change in body enzyme levels is common in such disorders.
Steroid therapy is must but steroids need to be tapered, else your bones will get affected.
Dont worry about rise in CPK levels.
Repeat the result after a week, if the value remains high or increases then there is need to increase the dose of steroid.
Let me know if you have any other doubts.
Thank you
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Dr. Rahul Kumar

Dermatologist

Practicing since :2010

Answered : 6640 Questions

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Should Steroid Dosage Be Increased For Increased CPK Levels?

Brief Answer: details of disease required Detailed Answer: Hello It is important for me to know why you were taking steroids daily. I will be able to comment on details regarding doses only after knowing the details of your disease. Thank you