
Suggest Alternative Medication In Place Of Oxcarbazepine

I haven't slept for so long. Sweating for 5 yrs. gotten worse. So u r saying I don't need to be on 30 mg for coristol. That's a relief. Yes I'm high manic depressive and on meds for that. But now my heart and lungs r affected. I'm deaf and always under stress. I don't know how I lived without coristol for two yrs till they found out. I don't get tired at all. That's a problem. The coristol dr Is frustrated with me and will not let me talk so he said to find another. No dr will listen. I'm deaf. The new heart dr is going to start over with me. I'm not being monitored. For 39 yrs the Drs have misdignosed me. I just want to live. No one is listening and letting me die. Which I almost did. I'm high depressive and take antidepressant. But the coristol I cannot take 39 mg without getting more sweating , vomiting, dizziness and no sleep. I'm scared. Been deaf so there is no patience from Drs. The heart dr said at least stay on one but I only say him once and is suppose to be good. I don't understand why I can't get anyone to do a work over once and for all after being misdignosed for 30 yrs. I somehow lost my memory. Not like what u think. It's like I can't remember what I said it did or what some else said or did an hour before. I can only go day to day trying to live but forget conversations. When I talk to friend my mind cuts right off in the middle of the conversation. It's strange. Who or where can I go to get this taken care of once and for all.
Drug dosage modification alone will improve your well being
Detailed Answer:
Hello, Madam.
I understand your concern.
Many of your symptoms are DIRECTLY related to the side effects of both medications.
You are currently on wrong medications as well as their doses.
The normal blood levels of cortisol to be maintained in the blood-
Morning--->5-23 micrograms per deciliter (mcg/dL) or 138-635 nanomoles per liter(nmol/l).
Afternoon---->3-16 mcg/dL or 83-441 nmol/L.
It is important that you maintain Cortisol in these levels only.
The dose of cortisol required on you case should be determined after having the therapeutic drug monitoring.
The usual maintenance dose of hydrocortisone in chronic adrenal insufficiency is 15-25 mg /day to be given in divided doses as 2-3 times a day.
In your case, it is better is maintain it as 15 mg/day to be taken as 7.5 mg q12hrly.
With regards to treatment for depression and manic episodes, it is advisable to prefer Carbamazepine to Oxcarbamazepine, since the later is associated with high side effect profile and is an off-label drug.
Likewise, it is good to keep the drug dose under 800 mg of CARBAMAZEPINE.This will minimize the side effects.
Please check with your physician if he shares my view and if can prescribe them to you.
Post your further queries if any.
Thank you.

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