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Suggest Remedies For Infertility In A Person With A History Of Tuberculosis
Question: Hello
I am 33 years old.I got married at 29 in 2012 and have been trying to conceive since then. I had a history of tuberculosis in my teens and had taken ATT twice in year 2000 and 2002. Before that I had dysmenorrhea after the onset of my periods which was taken care of after continuous bleeding of three months. I was detected with mild poly cystic ovaries after my ATT course.
I started my conception medication after six months of my marriage when I failed to conceive with clomiphene. I conceived in 3rd cycle of clomiphene and had a miscarriage at six weeks in 2013.
After that I tried several times with 6 more cycles of clomiphene with myoinositol also for my poly cystic ovaries for two years but everything failed.
Then I visited a renowned doctor in XXXXXXX Seeing everything he suggested that should go for ovarian drilling,lap XXXXXXX test and biopsy for my uterus.I did and my tubes were fine. Biopsy came normal.
So he suggested to start with clomiphene for three cycles.I did but to no avail though I had follicle sizes between 18-22 everytime.
Next he suggested for IUI.so I started with folliotropin injections and try it thrice. Again the same result.my husband's semen analysis had low count but it was normal after medication he received.
Next option I was left with was IVF.
I started that in August 2016 and had folliotropin injections and others too. I was hyperstimulated and almost had 27-28 follicles in both ovaries. After egg retrieval in august, he told us that I have got 16 embryos preserved in four sets. I got two transfers done in September 2016 and January 2017 but it failed again.The tragedy is that my husband passed away in March and a further visit to doctor confirmed that in March I conceived naturally but out of grief and stress I did not notice that I was pregnant so it dissolved.
I spoke to one my friend who also had a baby via IVF in XXXXXXX and she told me that my doctor did a mistake by keeping so many embryos in so little sets. It could have been more.
Can those sets be further divided? That is all I am left of
Please suggest something.
I am 33 years old.I got married at 29 in 2012 and have been trying to conceive since then. I had a history of tuberculosis in my teens and had taken ATT twice in year 2000 and 2002. Before that I had dysmenorrhea after the onset of my periods which was taken care of after continuous bleeding of three months. I was detected with mild poly cystic ovaries after my ATT course.
I started my conception medication after six months of my marriage when I failed to conceive with clomiphene. I conceived in 3rd cycle of clomiphene and had a miscarriage at six weeks in 2013.
After that I tried several times with 6 more cycles of clomiphene with myoinositol also for my poly cystic ovaries for two years but everything failed.
Then I visited a renowned doctor in XXXXXXX Seeing everything he suggested that should go for ovarian drilling,lap XXXXXXX test and biopsy for my uterus.I did and my tubes were fine. Biopsy came normal.
So he suggested to start with clomiphene for three cycles.I did but to no avail though I had follicle sizes between 18-22 everytime.
Next he suggested for IUI.so I started with folliotropin injections and try it thrice. Again the same result.my husband's semen analysis had low count but it was normal after medication he received.
Next option I was left with was IVF.
I started that in August 2016 and had folliotropin injections and others too. I was hyperstimulated and almost had 27-28 follicles in both ovaries. After egg retrieval in august, he told us that I have got 16 embryos preserved in four sets. I got two transfers done in September 2016 and January 2017 but it failed again.The tragedy is that my husband passed away in March and a further visit to doctor confirmed that in March I conceived naturally but out of grief and stress I did not notice that I was pregnant so it dissolved.
I spoke to one my friend who also had a baby via IVF in XXXXXXX and she told me that my doctor did a mistake by keeping so many embryos in so little sets. It could have been more.
Can those sets be further divided? That is all I am left of
Please suggest something.
Brief Answer:
Sets of 4 embryos are fine.
Detailed Answer:
Hi, I think freezing of 4 embryos per set is fine.
Generally, when you thaw the frozen embryos, some of them can't withstand the thawing and are not good enough for transfer. So, considering 4 embryos are frozen in one set, you can expect at least two or three to be good for transfer. This increases the chance of pregnancy.
If you want a single embryo transfer and 3 embryos are found to be good after thawing one set of embryos, you can ask the embryologist to freeze the rest.
I think you can go for an endometrial biopsy for natural killer cells. If natural killer cells are high, you can take grafile instillation into the uterus before embryo transfer.
You can also go fo an ERA test to find out the best day on which your endometrium is receptive. This is a costly test, but worth. Talk to your doctor regarding this.
Hope this helps. If you have any other query, I will be happy to help.
Regards
Sets of 4 embryos are fine.
Detailed Answer:
Hi, I think freezing of 4 embryos per set is fine.
Generally, when you thaw the frozen embryos, some of them can't withstand the thawing and are not good enough for transfer. So, considering 4 embryos are frozen in one set, you can expect at least two or three to be good for transfer. This increases the chance of pregnancy.
If you want a single embryo transfer and 3 embryos are found to be good after thawing one set of embryos, you can ask the embryologist to freeze the rest.
I think you can go for an endometrial biopsy for natural killer cells. If natural killer cells are high, you can take grafile instillation into the uterus before embryo transfer.
You can also go fo an ERA test to find out the best day on which your endometrium is receptive. This is a costly test, but worth. Talk to your doctor regarding this.
Hope this helps. If you have any other query, I will be happy to help.
Regards
Above answer was peer-reviewed by :
Dr. Yogesh D
where do you suggest I can get the ERA test done in XXXXXXX and how much would it cost?
Brief Answer:
It will cost around 30,000.
Detailed Answer:
Hi, I think you can visit any reputed fertility centre like XXXXXXX IVI, Birth Fertility centre or XXXXXXX IVF. You can also search on internet regarding this.
Cost will be around 30,000.
Hope it helps.
It will cost around 30,000.
Detailed Answer:
Hi, I think you can visit any reputed fertility centre like XXXXXXX IVI, Birth Fertility centre or XXXXXXX IVF. You can also search on internet regarding this.
Cost will be around 30,000.
Hope it helps.
Above answer was peer-reviewed by :
Dr. Kampana
My one set of frozen embryos have 3-4 embryos.can I get a single embryo transfer done from one set and preserve the rest. I suggested this to my doctor but he says it's not possible as it may affect the quality. I have only two sets and can't take much chance as my husband is no more.what do you suggest?
Brief Answer:
Hi, you have to wait till thawing.
Detailed Answer:
Hi, I think you have to wait till thawing of embryos. It depends on the quality of embryos and number of embryos survived after thawing. So, I think after thawing only, your doctor will be able to tell you regarding this.
So, I think you should wait until that.
The survival rate of one time frozen embryos is 76 percent and twice frozen embryos is 74 percent. Various studies are available on internet regarding this.
The implantation rate and pregnancy rate is also not very different.
So, talk to your embryologist once your embryos are thawed.
Hope I have answered your question. If you have any other query, I will be happy to help.
Hi, you have to wait till thawing.
Detailed Answer:
Hi, I think you have to wait till thawing of embryos. It depends on the quality of embryos and number of embryos survived after thawing. So, I think after thawing only, your doctor will be able to tell you regarding this.
So, I think you should wait until that.
The survival rate of one time frozen embryos is 76 percent and twice frozen embryos is 74 percent. Various studies are available on internet regarding this.
The implantation rate and pregnancy rate is also not very different.
So, talk to your embryologist once your embryos are thawed.
Hope I have answered your question. If you have any other query, I will be happy to help.
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Above answer was peer-reviewed by :
Dr. Prasad
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