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Suggest Remedy For Muscle Spasms When On Wellbutrin
Question: I already wrote a question . The question was a follow up to my earlier question. I am an adult woman with CP. I am, on an anti-spasmodic drug Zanaflex. I asked an earlier doctor if he/she knew of an anti-depressant least likely to aggravate my spasms. I've tried about every SSRI and have now stared again I was prescribed Wellburin buts it caused spasms. I am now in my first week of Wellbutrin on half dose going up to a full dose of 15mg. and it is already causing spasms. Hence, my question, Which non-SSRIs are least likely to cause muscle spasms?
Brief Answer:
Agomelatin would not cause much spasms
Detailed Answer:
Hello thanks for asking from HCM for your health related queries
I can understand your concern. A lot of drugs can increase muscle spasms in patients of Cerebral Palsy. If we consider anti-depressants then SSRIs are considered as safe for spasms but you have developed spasm with that medicines also. Wellbutrin is known to aggravate spasticity so there is not use in taking that drug more.
Medicines like Agomelatin can be used in your case as it would be safe in spasticity. A lot of studies has found it to be safe antidepressant drug though in practical use it is not efficacious as other SSRIs.
Newer anti depressants like Vortioxetine can also be tried. The drug is a serotonergic drug with actions different than SSRIs. This is not known to cause much spasticity though much studies are lacking. The drug should be started with low doses.
Apart from this start supplements containing B12 vitamin and Omega-3-Fatty Acids along with your medicines. These supplements will supplement the action of anti-depressants and would not cause spasms.
Consult your psychiatrist for these medicines and take the drugs with proper prescription only.
Thanks, hope this helps you. Ask again for more doubts.
Agomelatin would not cause much spasms
Detailed Answer:
Hello thanks for asking from HCM for your health related queries
I can understand your concern. A lot of drugs can increase muscle spasms in patients of Cerebral Palsy. If we consider anti-depressants then SSRIs are considered as safe for spasms but you have developed spasm with that medicines also. Wellbutrin is known to aggravate spasticity so there is not use in taking that drug more.
Medicines like Agomelatin can be used in your case as it would be safe in spasticity. A lot of studies has found it to be safe antidepressant drug though in practical use it is not efficacious as other SSRIs.
Newer anti depressants like Vortioxetine can also be tried. The drug is a serotonergic drug with actions different than SSRIs. This is not known to cause much spasticity though much studies are lacking. The drug should be started with low doses.
Apart from this start supplements containing B12 vitamin and Omega-3-Fatty Acids along with your medicines. These supplements will supplement the action of anti-depressants and would not cause spasms.
Consult your psychiatrist for these medicines and take the drugs with proper prescription only.
Thanks, hope this helps you. Ask again for more doubts.
Note: For further guidance on mental health, Click here.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
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