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Suggest Treatment For Hemangiopericytoma
Question: my hbsag eclia# is 244.20 total bilirubin 1.40 direct biliubrin 0.90 sgopt 1040 sgpt 1381.00 alkine phosphate 778 ag ratio 1.10. my left lobe liver was resected at XXXXXXX on 1.7.2014. for suspected HCC ,with heamengioparicytoma as histopath report. what should i do ? pl advise. ultrasound abd is unremarkable Pet scan done on 22.08.2014 is also clear with N A D remark.BEFORE AND AFTER MY LIVER SURGERY ON 1.7.2014 ALL PATHOLOGICAL TESTS INCLUDING LFT KFT ALL VIRAL MARKERS ALFA FETOPROTINE AND ENDOSCOPY WERE NORMAL.I WAS GIVEN ONE POINT OF BLOOD TRANSFUSION DURING SURGERY. PL ADVISE
Brief Answer:
Confirmatory tests required
Detailed Answer:
Thanks for asking on Healthcaremagic.
Hemangiopericytoma is a type of soft tissue sarcoma (a type of tumor) that originates in the pericytes (a type of lining cells) in the walls of capillaries. They have a high rate of recurrence and metastases (spread to distant parts). Depending of the grade of the sarcoma, it is treated with surgery, chemotherapy and/or radiotherapy. It is different from hepatocellular carcinoma (HCC). You should immediately get in touch with an oncologist (cancer specialist) and proceed as per his directions.
Hepatitis C Electrochemiluminescence Immunoassay (ECLIA) is a test to detect antibodies to hepatitis C virus (anti-HCV). Although levels above 200 are considered positive, it needs to be confirmed using two other methods Chemiluminescent Microparticle Immunoassay (CMIA), Microparticle Enzyme Immunoassay (MEIA). This is because false positive results could also occur in one of these tests. So you need not jump to conclusions at the moment. Please get these tests done. In any case, Hepatitis C is unrelated to development of your hemangiopericytoma but HCC if present, could be related to Hepatitis C.
As I told, I would not like to jump to conclusions without the confirmatory tests done, more so because all the viral markers are negative.
Wish you all the best.
Regards
Confirmatory tests required
Detailed Answer:
Thanks for asking on Healthcaremagic.
Hemangiopericytoma is a type of soft tissue sarcoma (a type of tumor) that originates in the pericytes (a type of lining cells) in the walls of capillaries. They have a high rate of recurrence and metastases (spread to distant parts). Depending of the grade of the sarcoma, it is treated with surgery, chemotherapy and/or radiotherapy. It is different from hepatocellular carcinoma (HCC). You should immediately get in touch with an oncologist (cancer specialist) and proceed as per his directions.
Hepatitis C Electrochemiluminescence Immunoassay (ECLIA) is a test to detect antibodies to hepatitis C virus (anti-HCV). Although levels above 200 are considered positive, it needs to be confirmed using two other methods Chemiluminescent Microparticle Immunoassay (CMIA), Microparticle Enzyme Immunoassay (MEIA). This is because false positive results could also occur in one of these tests. So you need not jump to conclusions at the moment. Please get these tests done. In any case, Hepatitis C is unrelated to development of your hemangiopericytoma but HCC if present, could be related to Hepatitis C.
As I told, I would not like to jump to conclusions without the confirmatory tests done, more so because all the viral markers are negative.
Wish you all the best.
Regards
Above answer was peer-reviewed by :
Dr. Vinay Bhardwaj
Respected Doctor Sir ,
I have not received answer to my actual question. My question was that in the recent tests which I got done, my HBsAg (e-CLIA) IS 244.20, total bilirubin 1.40,direct biliubrin 0.90, sgopt 1040, sgpt 1381.00, alkine phosphate 778 & AG ratio is 1.10. .WHAT TO DO IN THE LIGHT OF THIS ELEVATED & ALARMED HBSAG & SGOPT & SGPT.
My left lobe liver was resected at XXXXXXX on 1.7.2014.
You have in your reply touched Hepatits c whereas my problem is Hepatits B WHICH IS 244.20. MY REQUEST WAS ACTUALLY TO KNOW HOW SERIOUS IS THIS CONDITION & WHAT TREATMENT IS SUGGESTED FOR CURE OF THIS PROBLEM
PL ADVISE TREATMENT FOR THIS PROBLEM. CAN I GET MYSELF VACCINATED FOR HEPATITS B AT THIS POINT OF TIME.
Thanks & Regards
I have not received answer to my actual question. My question was that in the recent tests which I got done, my HBsAg (e-CLIA) IS 244.20, total bilirubin 1.40,direct biliubrin 0.90, sgopt 1040, sgpt 1381.00, alkine phosphate 778 & AG ratio is 1.10. .WHAT TO DO IN THE LIGHT OF THIS ELEVATED & ALARMED HBSAG & SGOPT & SGPT.
My left lobe liver was resected at XXXXXXX on 1.7.2014.
You have in your reply touched Hepatits c whereas my problem is Hepatits B WHICH IS 244.20. MY REQUEST WAS ACTUALLY TO KNOW HOW SERIOUS IS THIS CONDITION & WHAT TREATMENT IS SUGGESTED FOR CURE OF THIS PROBLEM
PL ADVISE TREATMENT FOR THIS PROBLEM. CAN I GET MYSELF VACCINATED FOR HEPATITS B AT THIS POINT OF TIME.
Thanks & Regards
Brief Answer:
Vaccination at this point of time would not help
Detailed Answer:
Thanks for writing back.
Let me apologize for mentioning Hepatitis C mistakenly instead of Hepatitis B. But the statements remains valid (just replace C with B).
I was talking about confirmation first. In case, I am to take the assumption of Hepatitis B positivity, it can either progress to acute fulminant hepatitis or may take a chronic form. In your case, it is not the acute fulminant form. Although the elevation of liver enzymes could indicate development of a chronic form but it could also be due to the unrelated hangiopericytoma. Generally antivirals are prescribed to bring the infection in control. The net result is negativity of the serum markers. But in your case the markers being already negative raises a question whether the diagnosis is dependable.
At the moment I would not suggest any intervention to bring down the liver enzymes. Although ECLIA is positive, I am not confirm about the diagnosis and hence did not comment on the severity. Discuss about the two tests that I mentioned in my previous reply (CMIA / MEIA) with your treating doctor. If the diagnosis gets confirmed, antivirals are to be given and would bring the infection in control. Depending upon the specific scenario, interferons may be required.
Vaccine for Hepatitis B would not be effective if you take it now.
I understand that you are in a puzzling situation. Let me ascertain you that even if you are diagnosed to have Hepatitis B, you can have a absolutely normal life though on medication.
Wishing you health.
Regards
Vaccination at this point of time would not help
Detailed Answer:
Thanks for writing back.
Let me apologize for mentioning Hepatitis C mistakenly instead of Hepatitis B. But the statements remains valid (just replace C with B).
I was talking about confirmation first. In case, I am to take the assumption of Hepatitis B positivity, it can either progress to acute fulminant hepatitis or may take a chronic form. In your case, it is not the acute fulminant form. Although the elevation of liver enzymes could indicate development of a chronic form but it could also be due to the unrelated hangiopericytoma. Generally antivirals are prescribed to bring the infection in control. The net result is negativity of the serum markers. But in your case the markers being already negative raises a question whether the diagnosis is dependable.
At the moment I would not suggest any intervention to bring down the liver enzymes. Although ECLIA is positive, I am not confirm about the diagnosis and hence did not comment on the severity. Discuss about the two tests that I mentioned in my previous reply (CMIA / MEIA) with your treating doctor. If the diagnosis gets confirmed, antivirals are to be given and would bring the infection in control. Depending upon the specific scenario, interferons may be required.
Vaccine for Hepatitis B would not be effective if you take it now.
I understand that you are in a puzzling situation. Let me ascertain you that even if you are diagnosed to have Hepatitis B, you can have a absolutely normal life though on medication.
Wishing you health.
Regards
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Above answer was peer-reviewed by :
Dr. Prasad
Answered by
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