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Suggest Treatment For Hepatitis-B Infection

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Posted on Mon, 23 Jan 2017
Question: Hello doctor,
My Hbs ag is Positive , Hbe ag negative .
Anti Hbe Ag position .
ALT(SGPT) is 17.

What can I do now?
Is there any cure of Hbs ag?
doctor
Answered by Dr. Panagiotis Zografakis (26 minutes later)
Brief Answer:
more information please...

Detailed Answer:
Hello,

tests can be interpreted in the clinical context only. Otherwise only assumptions can be made. So please clarify the following:
- had you been vaccinated for hepatitis B? When?
- have you ever got acute hepatitis B (jaundice, right quadrant pain, fever, brown urine, no appetite, etc) ? When?
- do you use illicit drugs? Do you share needles if you do?
- have you ever had any blood transfusions?
- finally, have you ever had unprotected sex with partners of unknown hepatitis status?

A positive HBsAg without history of hepatitis can be even false positive. If you did have clinical syndrome then it can be chronic hepatitis because that's when HBsAg remains positive but the rest of the markers may become negative. Having negative antibodies is a little strange though.

Please upload all the test reports and answer the clinical questions to help me give you a better interpretation of your situation.

Kind Regards!
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Panagiotis Zografakis (2 days later)
Here the reports
doctor
Answered by Dr. Panagiotis Zografakis (1 hour later)
Brief Answer:
not enough information still

Detailed Answer:
Thanks for the additional information but it's not what I asked for. I asked for all the reports and some clinical data. Anyway, I'll give you an answer based on what you've told me so far.

A positive HBsAg without positive antiHBc may mean any of the following:
- false positive HBsAg (no sign of hepatitis)
- false negative AntiHBc (hepatitis present but not completely evident in serologic testing
- wild type hepatitis virus with altered genetic content resulting in variable serologic results
- immune deficiency resulting in lack of responsiveness to HBcAg due to HIV coinfection, cancer, lymphomas, etc

You have to confirm the serologic results, do the HBV-DNA test and if hepatitis is confirmed, your doctor has to find out which of the aforementioned conditions fits your case. The most likely scenario is chronic hepatitis.

I hope it helps!
Happy new year!
Note: For further follow up on digestive issues share your reports here and Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Panagiotis Zografakis

Internal Medicine Specialist

Practicing since :1999

Answered : 3814 Questions

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Suggest Treatment For Hepatitis-B Infection

Brief Answer: more information please... Detailed Answer: Hello, tests can be interpreted in the clinical context only. Otherwise only assumptions can be made. So please clarify the following: - had you been vaccinated for hepatitis B? When? - have you ever got acute hepatitis B (jaundice, right quadrant pain, fever, brown urine, no appetite, etc) ? When? - do you use illicit drugs? Do you share needles if you do? - have you ever had any blood transfusions? - finally, have you ever had unprotected sex with partners of unknown hepatitis status? A positive HBsAg without history of hepatitis can be even false positive. If you did have clinical syndrome then it can be chronic hepatitis because that's when HBsAg remains positive but the rest of the markers may become negative. Having negative antibodies is a little strange though. Please upload all the test reports and answer the clinical questions to help me give you a better interpretation of your situation. Kind Regards!