Question: I am 55 y/o, post menopausal 10 years. I have Eylhr Danlos hypermobile with DDD and some significant arthritis in my spine. With the ED, I have had hypotension fluxuating with extreme high bp and tachycardia. My HR runs 120 at rest and I have woken up with rates of 160 to 180 in the morning. After reading dutch and british research on aging and ED, I found that clonidine seems to work for getting back to a normal HR. I am also on metroprolol and BP fluctuates from 170/139 to 70/40. When i was in my 3o's an alert doctor noted that I was having petite mal seizures lasting seconds to a few minutes. In the past year I have had IBS, migraine, projectile vomiting and worsening of erratic HR and BP. Most recently, I have lost my ability to taste food, it's all cardboard. And I have unexplained episodes of rage. I have a meningioma that isn't changing in size (discovered when in ER for vomiting and dehydration.) It has been suggested that I talk with my doc about an MR to look at my brain. Any ideas on aging with these issues? Someone suggested I research ME and other neurological symptoms.