Suggest Treatment For Myelofibrosis

Posted on Mon, 16 Oct 2017

Question: my mother has myelofibrosis. Her current hb level 8.2...platlet count and wbc count within normal limit bt spllen and liver enlarged..is there a cure? how should i take care of her?

Answered by Dr. Shailja Puri (41 minutes later)

Brief Answer:
Myelofibrosis does not have a cure yet. Management is supportive mainly

Detailed Answer:
Hello,
Thanks for posting your query on HealthcareMagic.

Myelofibrosis is an irreversible and progressive change in the bone marrow.
It may occur secondary to some other disorder or may be primary.

Myelofibrosis causes replacement of normal blood cells in bone marrow with fibrosis.
There is slow fall in hemoglobin, white blood cell count and platelets.

In response to decreased blood cell formation in bone marrow, blood cells start forming in spleen followed by liver. This is called extra-medullary hematopoiesis.

As rightly described by your doctor, management is primarily supportive aimed to maintain normal levels of hemoglobin, white blood cells, and platelets.

Few drugs are available to control or slow down myelofibrosis but a complete cure is not available.

If you more queries, I'll be glad to answer.

Thanks and take care
Dr. Shailja Puri

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Above answer was peer-reviewed by : Dr. Arnab Banerjee