Suggest Treatment For Nausea, Vomiting And Headaches
thank you.
possible by voriconazole
Detailed Answer:
Hi
Thanks for writing to us.
1. Voriconazole is not recommended for mucormycosis.
Amphoterecin B is the drug of choice. Many studies have reported that patients who are on voriconazole prophylaxis after Transplant get predisposed to mucormycosis. So in your child voriconazole could have promoted mucormycosis to dominate.
2. Renal failure is unlikely due to voriconazole. It usually causes liver injury and visual disturbance and no effect on kidney. Amphoterecin is a well known cause of renal injury.
3. Amphoterecin and antibiotics along with the mucormycosis by itself all put together could be responsible for the renal injury.
I do hope she is getting better now.
Wishing your child good health and speedy recovery.
Regards
Dr Arun
Could the combination of high dose steroids, antibiotics and antifungals place an immune deficient child at risk of polymicrobial (candida and mucor) blood infection.
At the time of infection, she had not received any antifungals for 48 hours.
possible
Detailed Answer:
Both the scenarios are possible.
Some kids may be sensitive to amphoterecin and renal failure can occur even in 3 days.
Steroids are well known to promote polymicrobial infection.
Regards